Details
| Original language | English |
|---|---|
| Pages (from-to) | 1602-1609 |
| Number of pages | 8 |
| Journal | Movement disorders |
| Volume | 39 |
| Issue number | 9 |
| Early online date | 26 Jul 2024 |
| Publication status | Published - Sept 2024 |
Abstract
Objective: The Progressive Supranuclear Palsy quality of life scale (PSP-QoL) has been shown to be a useful tool for capturing health-related quality of life of patients in “everyday life” and in progressive supranuclear palsy (PSP) research. However, at 45 items in length, the questionnaire can take a long time, exhausting PSP patients, in particular if cognitive impaired, which can have a negative impact on the assessment. The aim of this study was to establish a condensed version of the PSP-QoL for research and routine clinical care. Methods: In this retrospective study, data originating from a German cohort of PSP patients was analyzed. Data from 245 PSP patients were included in this study. The short PSP-QoL questionnaire was created using a two-factor solution and item-total and inter-item correlations for mental and physical aspects of daily living of the PSP-QoL followed by confirmatory factor analysis. Results: The final scale included 12 items representing mental (five items) and physical symptoms (seven items). The specified two-factor model displayed an excellent fit in the confirmatory factor analysis. The short Progressive Supranuclear Palsy Quality of Life scale (PSP-ShoQoL) correlated moderately with the PSP Rating Scale (r [243] = 0.514, P < 0.001) and Geriatric depression scale (r [231] = 0.548, P < 0.001). Sensitivity to change confirmed a significant decrease in QoL after 12 months. Discussion: In this study, we created a 12-item PSP-ShoQoL designed to “facilitate” daily clinical work that correlated strongly with the PSP-QoL and was sensitive to change.
Keywords
- health-related quality of life, progressive supranuclear palsy, PSP Quality of Life scale, rating scale
ASJC Scopus subject areas
- Neuroscience(all)
- Neurology
- Medicine(all)
- Clinical Neurology
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In: Movement disorders, Vol. 39, No. 9, 09.2024, p. 1602-1609.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - A Short Progressive Supranuclear Palsy Quality of Life Scale
AU - Jensen, Ida
AU - Stiel, Stephanie
AU - Bebermeier, Sarah
AU - Schrag, Anette
AU - Greten, Stephan
AU - Doll-Lee, Johanna
AU - Wegner, Florian
AU - Ye, Lan
AU - Heine, Johanne
AU - Krey, Lea
AU - Höllerhage, Matthias
AU - Patrick, S.
AU - Winkler, Jürgen
AU - Berg, Daniela
AU - Paschen, Steffen
AU - Tönges, Lars
AU - Gruber, Doreen
AU - Gandor, Florin
AU - Jost, Wolfgang H.
AU - Kühn, Andrea A.
AU - Claus, Inga
AU - Warnecke, Tobias
AU - Pedrosa, David J.
AU - Eggers, Carsten
AU - Trenkwalder, Claudia
AU - Classen, Joseph
AU - Schwarz, Johannes
AU - Pötter-Nerger, Monika
AU - Kassubek, Jan
AU - Schnitzler, Alfons
AU - Höglinger, Günter U.
AU - Klietz, Martin
N1 - Publisher Copyright: © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
PY - 2024/9
Y1 - 2024/9
N2 - Objective: The Progressive Supranuclear Palsy quality of life scale (PSP-QoL) has been shown to be a useful tool for capturing health-related quality of life of patients in “everyday life” and in progressive supranuclear palsy (PSP) research. However, at 45 items in length, the questionnaire can take a long time, exhausting PSP patients, in particular if cognitive impaired, which can have a negative impact on the assessment. The aim of this study was to establish a condensed version of the PSP-QoL for research and routine clinical care. Methods: In this retrospective study, data originating from a German cohort of PSP patients was analyzed. Data from 245 PSP patients were included in this study. The short PSP-QoL questionnaire was created using a two-factor solution and item-total and inter-item correlations for mental and physical aspects of daily living of the PSP-QoL followed by confirmatory factor analysis. Results: The final scale included 12 items representing mental (five items) and physical symptoms (seven items). The specified two-factor model displayed an excellent fit in the confirmatory factor analysis. The short Progressive Supranuclear Palsy Quality of Life scale (PSP-ShoQoL) correlated moderately with the PSP Rating Scale (r [243] = 0.514, P < 0.001) and Geriatric depression scale (r [231] = 0.548, P < 0.001). Sensitivity to change confirmed a significant decrease in QoL after 12 months. Discussion: In this study, we created a 12-item PSP-ShoQoL designed to “facilitate” daily clinical work that correlated strongly with the PSP-QoL and was sensitive to change.
AB - Objective: The Progressive Supranuclear Palsy quality of life scale (PSP-QoL) has been shown to be a useful tool for capturing health-related quality of life of patients in “everyday life” and in progressive supranuclear palsy (PSP) research. However, at 45 items in length, the questionnaire can take a long time, exhausting PSP patients, in particular if cognitive impaired, which can have a negative impact on the assessment. The aim of this study was to establish a condensed version of the PSP-QoL for research and routine clinical care. Methods: In this retrospective study, data originating from a German cohort of PSP patients was analyzed. Data from 245 PSP patients were included in this study. The short PSP-QoL questionnaire was created using a two-factor solution and item-total and inter-item correlations for mental and physical aspects of daily living of the PSP-QoL followed by confirmatory factor analysis. Results: The final scale included 12 items representing mental (five items) and physical symptoms (seven items). The specified two-factor model displayed an excellent fit in the confirmatory factor analysis. The short Progressive Supranuclear Palsy Quality of Life scale (PSP-ShoQoL) correlated moderately with the PSP Rating Scale (r [243] = 0.514, P < 0.001) and Geriatric depression scale (r [231] = 0.548, P < 0.001). Sensitivity to change confirmed a significant decrease in QoL after 12 months. Discussion: In this study, we created a 12-item PSP-ShoQoL designed to “facilitate” daily clinical work that correlated strongly with the PSP-QoL and was sensitive to change.
KW - health-related quality of life
KW - progressive supranuclear palsy
KW - PSP Quality of Life scale
KW - rating scale
UR - http://www.scopus.com/inward/record.url?scp=85199873282&partnerID=8YFLogxK
U2 - 10.1002/mds.29936
DO - 10.1002/mds.29936
M3 - Article
C2 - 39056204
AN - SCOPUS:85199873282
VL - 39
SP - 1602
EP - 1609
JO - Movement disorders
JF - Movement disorders
SN - 0885-3185
IS - 9
ER -