Details
| Original language | English |
|---|---|
| Pages (from-to) | 863-865 |
| Number of pages | 3 |
| Journal | SYNLETT |
| Issue number | 5 |
| Publication status | Published - 21 Mar 2005 |
Abstract
The rapid assembly of polyketide segments remains one central task in the field of natural product synthesis. Besides the stereoselective assembly of carbon frameworks functional group transformations and protecting group manipulations have to be optimized in order to streamline organic synthesis. The activated aldehyde derived from Jung's non aldol-aldol method serves as an intermediate for the subsequent vinylogous Mukaiyama aldol reaction.
Keywords
- Aldol, Rearrangement, Semi-pinacol, Vinylogous
ASJC Scopus subject areas
- Chemistry(all)
- Organic Chemistry
Cite this
- Standard
- Harvard
- Apa
- Vancouver
- BibTeX
- RIS
In: SYNLETT, No. 5, 21.03.2005, p. 863-865.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - A one-pot non-aldol-aldol vinylogous Mukaiyama aldol tandem sequence for the rapid construction of polyketide frameworks
AU - Rahn, Nicola
AU - Kalesse, Markus
PY - 2005/3/21
Y1 - 2005/3/21
N2 - The rapid assembly of polyketide segments remains one central task in the field of natural product synthesis. Besides the stereoselective assembly of carbon frameworks functional group transformations and protecting group manipulations have to be optimized in order to streamline organic synthesis. The activated aldehyde derived from Jung's non aldol-aldol method serves as an intermediate for the subsequent vinylogous Mukaiyama aldol reaction.
AB - The rapid assembly of polyketide segments remains one central task in the field of natural product synthesis. Besides the stereoselective assembly of carbon frameworks functional group transformations and protecting group manipulations have to be optimized in order to streamline organic synthesis. The activated aldehyde derived from Jung's non aldol-aldol method serves as an intermediate for the subsequent vinylogous Mukaiyama aldol reaction.
KW - Aldol
KW - Rearrangement
KW - Semi-pinacol
KW - Vinylogous
UR - http://www.scopus.com/inward/record.url?scp=15944393193&partnerID=8YFLogxK
U2 - 10.1055/s-2005-863743
DO - 10.1055/s-2005-863743
M3 - Article
AN - SCOPUS:15944393193
SP - 863
EP - 865
JO - SYNLETT
JF - SYNLETT
SN - 0936-5214
IS - 5
ER -