Details
| Original language | English |
|---|---|
| Pages (from-to) | 3845-3851 |
| Number of pages | 7 |
| Journal | Langmuir |
| Volume | 28 |
| Issue number | 8 |
| Publication status | Published - 7 Feb 2012 |
| Externally published | Yes |
Abstract
One of the most toxic byproducts of nuclear power and weapons production is the transuranics, which have a high radiotoxicity and long biological half-life due to their tendency to accumulate in the skeletal system. This accumulation is inhomogeneous and has been associated with the chemical properties and structure of the bone material rather than its location or function. This suggests a chemical driving force to incorporation and requires an atomic scale mechanistic understanding of the incorporation process. Here we propose a new incorporation mechanism for trivalent actinides and lanthanides into synthetic and biologically produced hydroxyapatite. Time-resolved laser fluorescence spectroscopy and extended X-ray absorption fine structure have been used to demonstrate that trivalent actinides and lanthanides incorporate into the amorphous grain boundaries of apatite. This incorporation site can be used to explain patterns in uptake and distribution of radionuclides in the mammalian skeletal system.
ASJC Scopus subject areas
- Materials Science(all)
- General Materials Science
- Physics and Astronomy(all)
- Condensed Matter Physics
- Physics and Astronomy(all)
- Surfaces and Interfaces
- Chemistry(all)
- Spectroscopy
- Chemistry(all)
- Electrochemistry
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In: Langmuir, Vol. 28, No. 8, 07.02.2012, p. 3845-3851.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - A new incorporation mechanism for trivalent actinides into bioapatite
T2 - A TRLFS and EXAFS study
AU - Holliday, Kiel
AU - Handley-Sidhu, Stephanie
AU - Dardenne, Kathy
AU - Renshaw, Joanna
AU - Macaskie, Lynne
AU - Walther, Clemens
AU - Stumpf, Thorsten
PY - 2012/2/7
Y1 - 2012/2/7
N2 - One of the most toxic byproducts of nuclear power and weapons production is the transuranics, which have a high radiotoxicity and long biological half-life due to their tendency to accumulate in the skeletal system. This accumulation is inhomogeneous and has been associated with the chemical properties and structure of the bone material rather than its location or function. This suggests a chemical driving force to incorporation and requires an atomic scale mechanistic understanding of the incorporation process. Here we propose a new incorporation mechanism for trivalent actinides and lanthanides into synthetic and biologically produced hydroxyapatite. Time-resolved laser fluorescence spectroscopy and extended X-ray absorption fine structure have been used to demonstrate that trivalent actinides and lanthanides incorporate into the amorphous grain boundaries of apatite. This incorporation site can be used to explain patterns in uptake and distribution of radionuclides in the mammalian skeletal system.
AB - One of the most toxic byproducts of nuclear power and weapons production is the transuranics, which have a high radiotoxicity and long biological half-life due to their tendency to accumulate in the skeletal system. This accumulation is inhomogeneous and has been associated with the chemical properties and structure of the bone material rather than its location or function. This suggests a chemical driving force to incorporation and requires an atomic scale mechanistic understanding of the incorporation process. Here we propose a new incorporation mechanism for trivalent actinides and lanthanides into synthetic and biologically produced hydroxyapatite. Time-resolved laser fluorescence spectroscopy and extended X-ray absorption fine structure have been used to demonstrate that trivalent actinides and lanthanides incorporate into the amorphous grain boundaries of apatite. This incorporation site can be used to explain patterns in uptake and distribution of radionuclides in the mammalian skeletal system.
UR - http://www.scopus.com/inward/record.url?scp=84857676401&partnerID=8YFLogxK
U2 - 10.1021/la300014a
DO - 10.1021/la300014a
M3 - Article
C2 - 22313032
AN - SCOPUS:84857676401
VL - 28
SP - 3845
EP - 3851
JO - Langmuir
JF - Langmuir
SN - 0743-7463
IS - 8
ER -