Details
| Original language | English |
|---|---|
| Pages (from-to) | 325-331 |
| Number of pages | 7 |
| Journal | Records of natural products |
| Volume | 7 |
| Issue number | 4 |
| Publication status | Published - 14 Aug 2013 |
| Externally published | Yes |
Abstract
Phytochemical investigation of the aerial parts of Senecio desfontainei afforded one new benzoxepin derivative, Senecioside (1) along with eleven known compounds (2-12). Their structures were assigned from H and C NMR spectra, DEPT and by 2D COSY, NOE, HSQC and HMBC experiments. All these compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 2, 3, 4, 6 and 9 showed significant antioxidant activity against DPPH radicals.
Keywords
- Antioxidant activity, Compositae, Senecio desfontainei, Senecioside
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmacology
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Agricultural and Biological Sciences(all)
- Plant Science
- Chemistry(all)
- Organic Chemistry
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In: Records of natural products, Vol. 7, No. 4, 14.08.2013, p. 325-331.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - A new bezoxepin derivative from Senecio desfontainei
AU - Hamid Hussain, Syed
AU - Latif, Abdul
AU - Arfan, Mohammad
AU - Ali, Mumtaz
AU - Simpson, Thomos J.
AU - Cox, Russell J.
AU - Shaheen, Farzana
AU - Uddin, Ghias
PY - 2013/8/14
Y1 - 2013/8/14
N2 - Phytochemical investigation of the aerial parts of Senecio desfontainei afforded one new benzoxepin derivative, Senecioside (1) along with eleven known compounds (2-12). Their structures were assigned from H and C NMR spectra, DEPT and by 2D COSY, NOE, HSQC and HMBC experiments. All these compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 2, 3, 4, 6 and 9 showed significant antioxidant activity against DPPH radicals.
AB - Phytochemical investigation of the aerial parts of Senecio desfontainei afforded one new benzoxepin derivative, Senecioside (1) along with eleven known compounds (2-12). Their structures were assigned from H and C NMR spectra, DEPT and by 2D COSY, NOE, HSQC and HMBC experiments. All these compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 2, 3, 4, 6 and 9 showed significant antioxidant activity against DPPH radicals.
KW - Antioxidant activity
KW - Compositae
KW - Senecio desfontainei
KW - Senecioside
UR - http://www.scopus.com/inward/record.url?scp=84881265143&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84881265143
VL - 7
SP - 325
EP - 331
JO - Records of natural products
JF - Records of natural products
SN - 1307-6167
IS - 4
ER -