Details
| Original language | English |
|---|---|
| Title of host publication | Lecture Notes in Applied and Computational Mechanics |
| Publisher | Springer Verlag |
| Pages | 257-272 |
| Number of pages | 16 |
| Publication status | Published - 31 Aug 2017 |
Publication series
| Name | Lecture Notes in Applied and Computational Mechanics |
|---|---|
| Volume | 84 |
| ISSN (Print) | 1613-7736 |
Abstract
Streptococcus gordonii is one of the first colonizing bacteria on tooth or dental implant materials forming so-called biofilm. These biofilms cause severe inflammation that, as a consequence, lead to tooth or implant failure. A promising way to study the S. gordonii biofilm formation is by combining experimental investigations and numerical simulation. Our previous research has shown the potential to model the growth process of the S. gordonii biofilm in a mimic human oral environment by using a mathematical model developed by Alpkvist and Klapper (the A-K model). The parameters used for the simulation were calibrated by the experimental results. However, what are the crucial parameters that have a strong influence on the biofilm growth behavior and thus need to be determined accurately is an open question. In this paper, parameter studies on four independent parameters are carried out.
ASJC Scopus subject areas
- Engineering(all)
- Mechanical Engineering
- Computer Science(all)
- Computational Theory and Mathematics
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Lecture Notes in Applied and Computational Mechanics. Springer Verlag, 2017. p. 257-272 (Lecture Notes in Applied and Computational Mechanics; Vol. 84).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - A deeper insight of a multi-dimensional continuum biofilm growth model
T2 - Experimental observation and parameter studies
AU - Feng, Dianlei
AU - Rath, Henryke
AU - Neuweiler, Insa
AU - Stumpp, Nico
AU - Nackenhorst, Udo
AU - Stiesch, Meike
N1 - Funding information: Financial support of Dianlei Feng and Henryke Rath were provided by the Ministry of Science and Culture of Lower Saxony within the framework of the Doctoral Program MARIO (Multifunctional Active and Reactive Interfaces and Surfaces).
PY - 2017/8/31
Y1 - 2017/8/31
N2 - Streptococcus gordonii is one of the first colonizing bacteria on tooth or dental implant materials forming so-called biofilm. These biofilms cause severe inflammation that, as a consequence, lead to tooth or implant failure. A promising way to study the S. gordonii biofilm formation is by combining experimental investigations and numerical simulation. Our previous research has shown the potential to model the growth process of the S. gordonii biofilm in a mimic human oral environment by using a mathematical model developed by Alpkvist and Klapper (the A-K model). The parameters used for the simulation were calibrated by the experimental results. However, what are the crucial parameters that have a strong influence on the biofilm growth behavior and thus need to be determined accurately is an open question. In this paper, parameter studies on four independent parameters are carried out.
AB - Streptococcus gordonii is one of the first colonizing bacteria on tooth or dental implant materials forming so-called biofilm. These biofilms cause severe inflammation that, as a consequence, lead to tooth or implant failure. A promising way to study the S. gordonii biofilm formation is by combining experimental investigations and numerical simulation. Our previous research has shown the potential to model the growth process of the S. gordonii biofilm in a mimic human oral environment by using a mathematical model developed by Alpkvist and Klapper (the A-K model). The parameters used for the simulation were calibrated by the experimental results. However, what are the crucial parameters that have a strong influence on the biofilm growth behavior and thus need to be determined accurately is an open question. In this paper, parameter studies on four independent parameters are carried out.
UR - http://www.scopus.com/inward/record.url?scp=85028946842&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-59548-1_14
DO - 10.1007/978-3-319-59548-1_14
M3 - Contribution to book/anthology
AN - SCOPUS:85028946842
T3 - Lecture Notes in Applied and Computational Mechanics
SP - 257
EP - 272
BT - Lecture Notes in Applied and Computational Mechanics
PB - Springer Verlag
ER -