Details
| Original language | English |
|---|---|
| Pages (from-to) | 178-192 |
| Number of pages | 15 |
| Journal | GAMM Mitteilungen |
| Volume | 32 |
| Issue number | 2 |
| Publication status | Published - 2009 |
Abstract
In this presentation an integrated approach on the simulation of osseointegration in the boneimplant interface is outlined. Besides the consistent combination of computational bone remodelling simulation and established medical imaging techniques, a new model refinement in terms of a bioactive interface theory is introduced, which enables the simulation of bone ingrowth in rough coated uncemented implants. Under consideration of seven physiological loads of daily motion the bone-implant relative micromotion in a soft tissue region around the endoprosthesis is investigated. As the micromotions are an important factor for osseointegration, because excessive micromotion leads to apposition of fibrous tissue, they are considered for the simulation of osseointegration. Results for different parameter constellations, regarding thickness and stiffness of bone-implant interface layer, are compared and the ingrowth for different configurations is predicted. With these results conclusions can be made about the stability of prosthesis in the host bone, which is an important factor for the clinical success of the treatment.
Keywords
- Bone remodelling, Bone-implant interface, Finite element method, Hip-joint endoprosthesis, Implant stability, Micromotion, Osseointegration
ASJC Scopus subject areas
- Materials Science(all)
- General Materials Science
- Physics and Astronomy(all)
- General Physics and Astronomy
- Mathematics(all)
- Applied Mathematics
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In: GAMM Mitteilungen, Vol. 32, No. 2, 2009, p. 178-192.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - A computational approach on the osseointegration of bone implants based on a bio-active interface theory
AU - Lutz, André
AU - Nackenhorst, Udo
PY - 2009
Y1 - 2009
N2 - In this presentation an integrated approach on the simulation of osseointegration in the boneimplant interface is outlined. Besides the consistent combination of computational bone remodelling simulation and established medical imaging techniques, a new model refinement in terms of a bioactive interface theory is introduced, which enables the simulation of bone ingrowth in rough coated uncemented implants. Under consideration of seven physiological loads of daily motion the bone-implant relative micromotion in a soft tissue region around the endoprosthesis is investigated. As the micromotions are an important factor for osseointegration, because excessive micromotion leads to apposition of fibrous tissue, they are considered for the simulation of osseointegration. Results for different parameter constellations, regarding thickness and stiffness of bone-implant interface layer, are compared and the ingrowth for different configurations is predicted. With these results conclusions can be made about the stability of prosthesis in the host bone, which is an important factor for the clinical success of the treatment.
AB - In this presentation an integrated approach on the simulation of osseointegration in the boneimplant interface is outlined. Besides the consistent combination of computational bone remodelling simulation and established medical imaging techniques, a new model refinement in terms of a bioactive interface theory is introduced, which enables the simulation of bone ingrowth in rough coated uncemented implants. Under consideration of seven physiological loads of daily motion the bone-implant relative micromotion in a soft tissue region around the endoprosthesis is investigated. As the micromotions are an important factor for osseointegration, because excessive micromotion leads to apposition of fibrous tissue, they are considered for the simulation of osseointegration. Results for different parameter constellations, regarding thickness and stiffness of bone-implant interface layer, are compared and the ingrowth for different configurations is predicted. With these results conclusions can be made about the stability of prosthesis in the host bone, which is an important factor for the clinical success of the treatment.
KW - Bone remodelling
KW - Bone-implant interface
KW - Finite element method
KW - Hip-joint endoprosthesis
KW - Implant stability
KW - Micromotion
KW - Osseointegration
UR - http://www.scopus.com/inward/record.url?scp=73849089107&partnerID=8YFLogxK
U2 - 10.1002/gamm.200910015
DO - 10.1002/gamm.200910015
M3 - Article
AN - SCOPUS:73849089107
VL - 32
SP - 178
EP - 192
JO - GAMM Mitteilungen
JF - GAMM Mitteilungen
SN - 0936-7195
IS - 2
ER -