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Department of Biostatistics

Organisational unit: Section/Division

Type of address: Visitor address.
Herrenhäuser Straße 2
30419
Hannover
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Publications

  1. 2000
  2. Published

    One-sided simultaneous confidence intervals for effective dose steps in unbalanced designs

    Hothorn, L. A. & Bretz, F., 18 Dec 2000, In: Biometrical journal. 42, 8, p. 995-1006 12 p.

    Research output: Contribution to journalArticleResearchpeer review

  3. Published

    Evaluation of animal carcinogenicity studies: Cochran-armitage trend test vs. multiple contrast tests

    Hothorn, L. A. & Bretz, F., 5 Sept 2000, In: Biometrical journal. 42, 5, p. 553-567 15 p.

    Research output: Contribution to journalReview articleResearchpeer review

  4. Published

    Report and summary of the major conclusions from statistics in genotoxicity testing working group from the International Workshop on Genotoxicity Test Procedures (IWGTP), March 1999

    Lovell, D. P., Yoshimura, I., Hothorn, L. A., Margolin, B. H. & Soper Sandwich, S., 6 Jun 2000, In: Environmental and Molecular Mutagenesis. 35, 3, p. 260-263 4 p.

    Research output: Contribution to journalArticleResearchpeer review

  5. Published

    Parametric location-scale and scale trend tests based on Levene's transformation

    Neuhäuser, M. & Hothorn, L. A., 28 Apr 2000, In: Computational Statistics and Data Analysis. 33, 2, p. 189-200 12 p.

    Research output: Contribution to journalArticleResearchpeer review

  6. Published

    Dose-response relationships in mutagenicity assays including an appropriate positive control group: A multiple testing approach

    Hothorn, L. A., Hayashi, M. & Seidel, D., Mar 2000, In: Environmental and Ecological Statistics. 7, 1, p. 27-42 16 p.

    Research output: Contribution to journalArticleResearchpeer review

  7. Published

    Robust trend tests with application to toxicology

    Neuhäuser, M., Seidel, D., Hothorn, L. A. & Urfer, W., Mar 2000, In: Environmental and Ecological Statistics. 7, 1, p. 43-56 14 p.

    Research output: Contribution to journalArticleResearchpeer review

  8. Published

    Identifying the maximum safe dose: A multiple testing approach

    Hothorn, L. A. & Hauschke, D., 15 Feb 2000, In: Journal of Biopharmaceutical Statistics. 10, 1, p. 15-30 16 p.

    Research output: Contribution to journalArticleResearchpeer review

  9. 1999
  10. Published

    Trend tests in epidemiology: P-values or confidence intervals?

    Hothorn, L. A., 9 Nov 1999, In: Biometrical journal. 41, 7, p. 817-825 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  11. Published

    An exact Cochran-Armitage test for trend when dose-response shapes are a priori unknown

    Neuhäuser, M. & Hothorn, L. A., 28 Jun 1999, In: Computational Statistics and Data Analysis. 30, 4, p. 403-412 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  12. Published

    Proof of safety in toxicology based on the ratio of two means for normally distributed data

    Hauschke, D., Kieser, M. & Hothorn, L. A., 26 May 1999, In: Biometrical journal. 41, 3, p. 295-304 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. Published

    Nonparametric tests for trend: Jonckheere's test, a modification and a maximum test

    Neuhäuser, M., Liu, P. Y. & Hothorn, L. A., 19 Apr 1999, In: Biometrical journal. 40, 8, p. 899-909 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  14. 1998
  15. Published

    Biostatistical methodology in carcinogenicity studies

    Fairweather, W. R., Bhattacharyya, A., Ceuppens, P. P., Heimann, G., Hothorn, L. A., Kodell, R. L., Lin, K. K., Mager, H., Middleton, B. J., Slob, W., Soper, K. A., Stallard, N., Ventre, J. & Wright, J., 30 Dec 1998, In: Therapeutic Innovation & Regulatory Science. 32, 2, p. 401-421 21 p.

    Research output: Contribution to journalArticleResearchpeer review

  16. Published

    Testing strategies in multi-dose experiments including active control

    Bauer, P., Röhmel, J., Maurer, W. & Hothorn, L., 21 Dec 1998, In: Statistics in medicine. 17, 18, p. 2133-2146 14 p.

    Research output: Contribution to journalArticleResearchpeer review

  17. Published

    Lifelong administration of high doses of ibandronate increases bone mass and maintains bone quality of lumbar vertebrae in rats

    Lalla, S., Hothorn, L. A., Haag, N., Bader, R. & Bauss, F., Mar 1998, In: Osteoporosis international. 8, 2, p. 97-103 7 p.

    Research output: Contribution to journalArticleResearchpeer review

  18. 1997
  19. Published

    Application of adaptive interim analysis in pharmacology

    Hothorn, L. A. & Martin, U., 30 Dec 1997, In: Therapeutic Innovation & Regulatory Science. 31, 2, p. 615-619 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  20. Published

    Guest editor's note: Biostatistics in preclinical studies

    Hothorn, L. A., 30 Dec 1997, In: Therapeutic Innovation & Regulatory Science. 31, 2, p. 321-322 2 p.

    Research output: Contribution to journalArticleResearchpeer review

  21. Published

    Modifications of the closure principle for analyzing toxicological studies

    Hothorn, L. A., 30 Dec 1997, In: Therapeutic Innovation & Regulatory Science. 31, 2, p. 403-412 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  22. Published

    Multivariate many-to-one procedures with applications to preclinical trials

    Kropf, S., Hothorn, L. A. & Läuter, J., 30 Dec 1997, In: Therapeutic Innovation & Regulatory Science. 31, 2, p. 433-447 15 p.

    Research output: Contribution to journalArticleResearchpeer review

  23. Published

    The control of the consumer risk in the Ames assay

    Neuhäuser, M. & Hothorn, L. A., 30 Dec 1997, In: Drug Information Journal. 31, 2, p. 363-367 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  24. Published

    Trend tests for dichotomous endpoints with application to carcinogenicity studies

    Neuhäuser, M. & Hothorn, L. A., 30 Dec 1997, In: Therapeutic Innovation & Regulatory Science. 31, 2, p. 463-469 7 p.

    Research output: Contribution to journalArticleResearchpeer review