Publications
- E-pub ahead of print
Claiming trend in toxicological and pharmacological dose-response studies: an overview on statistical methods and related R-Software
Hothorn, L. A., 19 Jul 2020, (E-pub ahead of print).Research output: Working paper/Preprint › Preprint
- Published
Evaluation of incidence rates in pre-clinical studies using a williams-type procedure
Hothorn, L. A., Sill, M. & Schaarschmidt, F., 2010, In: International Journal of Biostatistics. 6, 1, 15.Research output: Contribution to journal › Article › Research › peer review
- Published
The two-step approach—a significant ANOVA F-test before Dunnett's comparisons against a control—is not recommended
Hothorn, L. A., 2 Jun 2016, In: Communications in Statistics - Theory and Methods. 45, 11, p. 3332-3343 12 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Statistical evaluation methods in toxicology
Hothorn, L. A., 5 Mar 2014, Regulatory Toxicology. p. 213-223 11 p.Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
- Published
Statistical evaluation of toxicological bioassays: A review
Hothorn, L. A., 8 Aug 2014, In: Toxicology research. 3, 6, p. 418-432 15 p.Research output: Contribution to journal › Review article › Research › peer review
- Published
Statistical analysis of the hen's egg test for micronucleus induction (HET-MN assay)
Hothorn, L. A., Reisinger, K., Wolf, T., Poth, A., Fieblinger, D., Liebsch, M. & Pirow, R., 18 Sept 2013, In: Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 757, 1, p. 68-78 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Model-specific tests on variance heterogeneity for detection of potentially interacting genetic loci
Hothorn, L. A., Libiger, O. & Gerhard, D., 18 Jul 2012, In: BMC genetics. 13, 59.Research output: Contribution to journal › Article › Research › peer review
- Published
A ratio-to-control Williams-type test for trend
Hothorn, L. A. & Djira, G. D., 11 Oct 2010, In: Pharmaceutical statistics. 10, 4, p. 289-292 4 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Order-restricted scores test for the evaluation of populationbased case-control studies when the genetic model is unknown
Hothorn, L. A. & Hothorn, T., 17 Aug 2009, In: Biometrical journal. 51, 4, p. 659-669 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Statistical evaluation of the in vivo micronucleus assay
Hothorn, L. A. & Gerhard, D., 9 Dec 2008, In: Archives of toxicology. 83, 6, p. 625-634 10 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Trend tests for the evaluation of exposure-response relationships in epidemiological exposure studies
Hothorn, L. A., Vaeth, M. & Hothorn, T., 6 Mar 2009, In: Epidemiologic Perspectives and Innovations. 6, 1, 1.Research output: Contribution to journal › Article › Research › peer review
- Published
Proof of hazard and proof of safety in toxicological studies using simultaneous confidence intervals for differences and ratios to control
Hothorn, L. A. & Hasler, M., 10 Sept 2008, In: Journal of Biopharmaceutical Statistics. 18, 5, p. 915-933 19 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Statistical Analysis of in Vivo Anticancer Experiments: Tumor Growth Inhibition
Hothorn, L. A., 30 Dec 2006, In: Therapeutic Innovation & Regulatory Science. 40, 2, p. 229-238 10 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Multiple comparisons and multiple contrasts in randomized dose-response trials: Confidence interval oriented approaches
Hothorn, L. A., 1 Oct 2006, In: Journal of Biopharmaceutical Statistics. 16, 5, p. 711-731 21 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Literature review non-clinical statistics: January-November 2005
Hothorn, L. A., 24 Feb 2006, In: Pharmaceutical statistics. 5, 1, p. 71-74 4 p.Research output: Contribution to journal › Review article › Research › peer review
- Published
Statistical analysis used in the nutritional assessment of novel food using the proof of safety
Hothorn, L. A. & Oberdoerfer, R., Mar 2006, In: Regulatory Toxicology and Pharmacology. 44, 2, p. 125-135 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Biostatistical Design and Analyses of Long-Term Animal Studies Simulating Human Postmenopausal Osteoporosis
Hothorn, L. A. & Bauss, F., 20 Dec 2004, In: Therapeutic Innovation & Regulatory Science. 38, 1, p. 47-56 10 p.Research output: Contribution to journal › Article › Research › peer review
- Published
A robust statistical procedure for evaluating genotoxicity data
Hothorn, L. A., 18 Aug 2004, In: ENVIRONMETRICS. 15, 6, p. 635-641 7 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Statistics of interlaboratory in vitro toxicological studies
Hothorn, L. A., Nov 2003, In: Alternatives to laboratory animals. 31, SUPPL. 1, p. 43-63 21 p.Research output: Contribution to journal › Review article › Research › peer review
- Published
Dose-response and thresholds in mutagenicity studies: A statistical testing approach
Hothorn, L. A. & Bretz, F., Nov 2003, In: Alternatives to laboratory animals. 31, SUPPL. 1, p. 97-103 7 p.Research output: Contribution to journal › Review article › Research › peer review