Publikationen
- 2003
Diastereoselective Synthesis of Cyclopropane Amino Acids Using Diazo Compounds Generated in Situ
Adams, L. A., Aggarwal, V. K., Bonnert, R. V., Bressel, B., Cox, R. J., Shepherd, J., De Vicente, J., Walter, M., Whittingham, W. G. & Winn, C. L., 28 Nov. 2003, in: Journal of Organic Chemistry. 68, 24, S. 9433-9440 8 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Rapid and flexible synthesis of 1-deoxy-D-xylulose-5-phosphate, the substrate for 1-deoxy-D-xylulose-5-phosphate reductoisomerase
Cox, R. J., De Andrés-Gómez, A. & Godfrey, C. R. A., 21 Sept. 2003, in: Organic and Biomolecular Chemistry. 1, 18, S. 3173-3177 5 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
The type I rat fatty acid synthase ACP shows structural homology and analogous biochemical properties to type II ACPs
Reed, M. A. C., Schweizer, M., Szafranska, A. E., Arthur, C., Nicholson, T. P., Cox, R. J., Crosby, J., Crump, M. P. & Simpson, T. J., 7 Feb. 2003, in: Organic and Biomolecular Chemistry. 1, 3, S. 463-471 9 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: Evidence for the mechanism of chain length determination
Nicholson, T. P., Winfield, C., Westcott, J., Crosby, J., Simpson, T. J. & Cox, R. J., 1 Jan. 2003, in: Chemical communications. 3, 6, S. 686-687 2 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
- 2002
Biosynthesis
Cox, R. J., 12 Dez. 2002, in: Annual Reports on the Progress of Chemistry - Section B. 98, S. 223-251 29 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Aspartyl phosphonates and phosphoramidates: The first synthetic inhibitors of bacterial aspartate-semialdehyde dehydrogenase
Cox, R. J., Gibson, J. S., Belén, M. & Martín, M., 1 Dez. 2002, in: CHEMBIOCHEM. 3, 9, S. 874-886 13 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Synthesis and characterisation of acyl carrier protein bound polyketide analogues
Arthur, C., Cox, R. J., Crosby, J., Rahman, M. M., Simpson, T. J., Soulas, F., Spogli, R., Szafranska, A. E., Westcott, J. & Winfield, C. J., 1 März 2002, in: CHEMBIOCHEM. 3, 2-3, S. 253-257 5 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site
Szafranska, A. E., Hitchman, T. S., Cox, R. J., Crosby, J. & Simpson, T. J., 5 Feb. 2002, in: Biochemistry. 41, 5, S. 1421-1427 7 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
A new synthesis of phosphoramidates: inhibitors of the key bacterial enzyme aspartate semi-aldehyde dehydrogenase
Adams, L. A., Cox, R. J., Gibson, J. S., Mayo-Martín, M. B., Walter, M. & Whittingham, W., 1 Jan. 2002, in: Chemical communications. 2, 18, S. 2004-2005 2 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Streptomyces coelicolor phosphopantetheinyl transferase: A promiscuous activator of polyketide and fatty acid synthase acyl carrier proteins
Cox, R. J., Crosby, J., Daltrop, O., Glod, F., Jarzabek, M. E., Nicholson, T. P., Reed, M., Simpson, T. J., Smith, L. H., Soulas, F., Szafranska, A. E. & Westcott, J., 1 Jan. 2002, in: Journal of the Chemical Society. Perkin Transactions 1. 14, S. 1644-1649 6 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Synthesis and in vitro enzyme activity of an oxa analogue of azi-DAP
Cox, R. J., Durston, J. & Roper, D. I., 1 Jan. 2002, in: Journal of the Chemical Society. Perkin Transactions 1. 8, S. 1029-1035 7 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
- Veröffentlicht
Biosynthesis
Cox, R. J., 2002, in: Annual Reports on the Progress of Chemistry - Section B.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
- 2001
Design and utility of oligonucleotide gene probes for fungal polyketide synthases
Nicholson, T. P., Rudd, B. A. M., Dawson, M., Lazarus, C. M., Simpson, T. J. & Cox, R. J., 1 Jan. 2001, in: Chemistry and Biology. 8, 2, S. 157-178 22 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Difluoromethylene analogues of aspartyl phosphate: The first synthetic inhibitors of aspartate semi-aldehyde dehydrogenase
Cox, R. J., Hadfield, A. T. & Mayo-Martín, M. B., 1 Jan. 2001, in: Chemical communications. 1, 18, S. 1710-1711 2 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Is N-acetylornithine aminotransferase the real N-succinyl-ll-diaminopimelate aminotransferase in Escherichia coli and Mycobacterium smegmatis?
Cox, R. J. & Wang, P. S. H., 1 Jan. 2001, in: Journal of the Chemical Society. Perkin Transactions 1. 1, 17, S. 2006-2008 3 S.Publikation: Beitrag in Fachzeitschrift › Meinungsbeitrag › Forschung › Peer-Review
Synthesis and in vitro enzyme activity of aza, oxa and thia derivatives of bacterial cell wall biosynthesis intermediates
Cox, R. J. & Wang, P. S. H., 1 Jan. 2001, in: Journal of the Chemical Society. Perkin Transactions 1. 1, 17, S. 2022-2034 13 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
- Veröffentlicht
Stoichiometric analysis of the minimal actinorhodin polyketide synthase system
Nettleship, J. E., Cox, R. J. & Simpson, T. J., 2001, in: Amino Acids (Vienna).Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
- 2000
Synthesis and in vitro enzyme activity of peptide derivatives of bacterial cell wall biosynthesis inhibitors
Cox, R. J., Jenkins, H., Schouten, J. A., Stentiford, R. A. & Wareing, K. J., 1 Dez. 2000, in: Journal of the Chemical Society, Perkin Transactions 1. 13, S. 2023-2036 14 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Bacterial diaminopimelate metabolism as a target for antibiotic design
Cox, R. J., Sutherland, A. & Vederas, J. C., Mai 2000, in: Bioorganic and Medicinal Chemistry. 8, 5, S. 843-871 29 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
Biosynthesis
Cox, R. J., 1 Jan. 2000, in: Annual Reports on the Progress of Chemistry - Section B. 2000, 96, S. 231-258 28 S.Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review