Profilinformationen

Prof. Dr.  Russell John Cox

Forschungs-netzwerk anzeigen

Publikationen

  1. 2007
  2. Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by Pseudomonas fluorescens: Pseudomonic acid B biosynthesis precedes pseudomonic acid A

    Hothersall, J., Wu, J., Rahman, A. S., Shields, J. A., Haddock, J., Johnson, N., Cooper, S. M., Stephens, E. R., Cox, R. J., Crosby, J., Willis, C. L., Simpson, T. J. & Thomas, C. M., 25 Mai 2007, in: Journal of Biological Chemistry. 282, 21, S. 15451-15461 11 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  3. An antibiotic produced by an insect-pathogenic bacterium suppresses host defenses through phenoloxidase inhibition

    Eleftherianos, I., Boundy, S., Joyce, S. A., Aslam, S., Marshall, J. W., Cox, R. J., Simpson, T. J., Clarke, D. J., Ffrench-Constant, R. H. & Reynolds, S. E., 13 Feb. 2007, in: Proceedings of the National Academy of Sciences of the United States of America. 104, 7, S. 2419-2424 6 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  4. Biosynthesis of the 2-pyridone tenellin in the insect pathogenic fungus Beauveria bassiana

    Eley, K. L., Halo, L. M., Song, Z., Powles, H., Cox, R. J., Bailey, A. M., Lazarus, C. M. & Simpson, T. J., 12 Feb. 2007, in: CHEMBIOCHEM. 8, 3, S. 289-297 9 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  5. Characterisation of 3-methylorcinaldehyde synthase (MOS) in Acremonium strictum: First observation of a reductive release mechanism during polyketide biosynthesis

    Bailey, A. M., Cox, R. J., Harley, K., Lazarus, C. M., Simpson, T. J. & Skellam, E., 1 Jan. 2007, in: Chemical communications. 39, S. 4053-4055 3 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  6. Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens

    Wu, J., Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Simpson, T. J., Thomas, C. M. & Willis, C. L., 1 Jan. 2007, in: Chemical communications. 20, S. 2040-2042 3 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  7. Polyketides, proteins and genes in fungi: Programmed nano-machines begin to reveal their secrets

    Cox, R. J., 1 Jan. 2007, in: Organic and Biomolecular Chemistry. 5, 13, S. 2010-2026 17 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  8. Acyl palladium species in synthesis: Single-step synthesis of α,β-unsaturated ketones from acid chlorides

    Cox, R. J. & Evitt, A. S., 2007, in: Organic and Biomolecular Chemistry. 5, 2, S. 229-232 4 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  9. Synthesis of [1,2-13C2,15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C

    Rees, D. O., Bushby, N., Cox, R. J., Harding, J. R., Simpson, T. J. & Willis, C. L., 2007, in: CHEMBIOCHEM. 8, 1, S. 46-50 5 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  10. 2006
  11. Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase

    Ma, Y., Smith, L. H., Cox, R. J., Beltran-Alvarez, P., Arthur, C. J. & Simpson, T. J., 1 Dez. 2006, in: CHEMBIOCHEM. 7, 12, S. 1951-1958 8 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  12. The Malonyl Transferase Activity of Type II Polyketide Synthase Acyl Carrier Proteins

    Arthur, C. J., Szafranska, A. E., Long, J., Mills, J., Cox, R. J., Findlow, S. C., Simpson, T. J., Crump, M. P. & Crosby, J., 1 Juni 2006, in: Chemistry and Biology. 13, 6, S. 587-596 10 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  13. 2005
  14. Design, synthesis and analysis of inhibitors of bacterial aspartate semialdehyde dehydrogenase

    Cox, R. J., Gibson, J. S. & Hadfield, A. T., 1 Dez. 2005, in: CHEMBIOCHEM. 6, 12, S. 2255-2260 6 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  15. A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase

    Mercklé, L., De Andrés-Gómez, A., Dick, B., Cox, R. J. & Godfrey, C. R. A., 1 Okt. 2005, in: CHEMBIOCHEM. 6, 10, S. 1866-1874 9 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  16. Shift to Pseudomonic Acid B Production in P. fluorescens NCIMB10586 by Mutation of Mupirocin Tailoring Genes mupO, mupU, mupV, and macpE

    Cooper, S. M., Laosripaiboon, W., Rahman, A. S., Hothersall, J., El-Sayed, A. K., Winfield, C., Crosby, J., Cox, R. J., Simpson, T. J. & Thomas, C. M., 1 Juli 2005, in: Chemistry and Biology. 12, 7, S. 825-833 9 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  17. Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster

    Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Laosripaiboon, W., Simpson, T. J. & Thomas, C. M., 7 März 2005, in: Chemical communications. 9, S. 1179-1181 3 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  18. Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes

    Cox, R. J., Ritson, D. J., Dane, T. A., Berge, J., Charmant, J. P. H. & Kantacha, A., 28 Feb. 2005, in: Chemical communications. 8, S. 1037-1039 3 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  19. Veröffentlicht

    Cloning fungal polyketide synthase genes: The fusarin and squalestatin synthases

    Cox, R., 2005, in: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  20. 2004
  21. Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis

    Cox, R. J., Glod, F., Hurley, D., Lazarus, C. M., Nicholson, T. P., Rudd, B. A. M., Simpson, T. J., Wilkinson, B. & Zhang, Y., 21 Okt. 2004, in: Chemical communications. 20, S. 2260-2261 2 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  22. Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum

    Song, Z., Cox, R. J., Lazarus, C. M. & Simpson, T. J., 6 Sept. 2004, in: CHEMBIOCHEM. 5, 9, S. 1196-1203 8 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  23. Indium mediated allylation of glyoxylate oxime ethers, esters and cyanoformates

    Ritson, D. J., Cox, R. J. & Berge, J., 7 Juli 2004, in: Organic and Biomolecular Chemistry. 2, 13, S. 1921-1933 13 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

  24. Expression, purification and preliminary X-ray diffraction analysis of a ketoreductase from a type II polyketide synthase

    Teartasin, W., Limpkin, C., Glod, F., Spencer, J., Cox, R. J., Simpson, T. J., Crosby, J., Crump, M. P. & Hadfield, A. T., 1 Juni 2004, in: Acta Crystallographica Section D: Biological Crystallography. 60, 6, S. 1137-1138 2 S.

    Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review