Well-posedness for a model of prion proliferation dynamics

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Philippe Laurençot
  • Christoph Walker

Externe Organisationen

  • Université Toulouse III – Paul Sabatier (UT3)
  • Vanderbilt University
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)241-264
Seitenumfang24
FachzeitschriftJournal of evolution equations
Jahrgang7
Ausgabenummer2
PublikationsstatusVeröffentlicht - Mai 2007
Extern publiziertJa

Abstract

The model considered consists of an ordinary differential equation coupled with an integro-partial differential equation and describes the interaction between non-infectious and infectious prion proteins. We provide sufficient conditions for uniqueness of monomer-preserving weak solutions. In addition, we also prove existence of weak solutions under rather general assumptions on the involved degradation rates.

ASJC Scopus Sachgebiete

Zitieren

Well-posedness for a model of prion proliferation dynamics. / Laurençot, Philippe; Walker, Christoph.
in: Journal of evolution equations, Jahrgang 7, Nr. 2, 05.2007, S. 241-264.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Laurençot P, Walker C. Well-posedness for a model of prion proliferation dynamics. Journal of evolution equations. 2007 Mai;7(2):241-264. doi: 10.1007/s00028-006-0279-2
Laurençot, Philippe ; Walker, Christoph. / Well-posedness for a model of prion proliferation dynamics. in: Journal of evolution equations. 2007 ; Jahrgang 7, Nr. 2. S. 241-264.
Download
@article{c861925caae5440a8d66ba98d7586fbc,
title = "Well-posedness for a model of prion proliferation dynamics",
abstract = "The model considered consists of an ordinary differential equation coupled with an integro-partial differential equation and describes the interaction between non-infectious and infectious prion proteins. We provide sufficient conditions for uniqueness of monomer-preserving weak solutions. In addition, we also prove existence of weak solutions under rather general assumptions on the involved degradation rates.",
keywords = "Existence, Prion proliferation, Uniqueness, Weak solutions",
author = "Philippe Lauren{\c c}ot and Christoph Walker",
note = "Funding information: Part of this work was done while the first author enjoyed the hospitality and support of the Helsinki University of Technology and the University of Helsinki, Finland, within the Finnish Mathematical Society Visitor Program in Mathematics 2005-2006 Function Spaces and Differential Equations.",
year = "2007",
month = may,
doi = "10.1007/s00028-006-0279-2",
language = "English",
volume = "7",
pages = "241--264",
journal = "Journal of evolution equations",
issn = "1424-3199",
publisher = "Birkhauser Verlag Basel",
number = "2",

}

Download

TY - JOUR

T1 - Well-posedness for a model of prion proliferation dynamics

AU - Laurençot, Philippe

AU - Walker, Christoph

N1 - Funding information: Part of this work was done while the first author enjoyed the hospitality and support of the Helsinki University of Technology and the University of Helsinki, Finland, within the Finnish Mathematical Society Visitor Program in Mathematics 2005-2006 Function Spaces and Differential Equations.

PY - 2007/5

Y1 - 2007/5

N2 - The model considered consists of an ordinary differential equation coupled with an integro-partial differential equation and describes the interaction between non-infectious and infectious prion proteins. We provide sufficient conditions for uniqueness of monomer-preserving weak solutions. In addition, we also prove existence of weak solutions under rather general assumptions on the involved degradation rates.

AB - The model considered consists of an ordinary differential equation coupled with an integro-partial differential equation and describes the interaction between non-infectious and infectious prion proteins. We provide sufficient conditions for uniqueness of monomer-preserving weak solutions. In addition, we also prove existence of weak solutions under rather general assumptions on the involved degradation rates.

KW - Existence

KW - Prion proliferation

KW - Uniqueness

KW - Weak solutions

UR - http://www.scopus.com/inward/record.url?scp=34247593078&partnerID=8YFLogxK

U2 - 10.1007/s00028-006-0279-2

DO - 10.1007/s00028-006-0279-2

M3 - Article

AN - SCOPUS:34247593078

VL - 7

SP - 241

EP - 264

JO - Journal of evolution equations

JF - Journal of evolution equations

SN - 1424-3199

IS - 2

ER -