TY - CHAP

T1 - Two-Photon Polymerization in Optics, Microfluidics, and Biomedicine

AU - El-Tamer, Ayman

AU - Hinze, Ulf

AU - Chichkov, Boris N.

PY - 2021/11/1

Y1 - 2021/11/1

N2 - Among the additive manufacturing processes, two-photon polymerization (TPP) is one of the most flexible and high-resolution processes of our time, as it enables the production of arbitrary three-dimensional structures on the basis of computer-aided design (CAD) models with a resolution of less than 100 nm. These properties open up new possibilities for the development of novel and miniaturized components for different applications, so that today TPP is successfully used in various areas of research. In this chapter we would like to cover the three largest areas of application of TPP, namely, optics, microfluidics, and biomedicine, and present interesting results that should give the reader a deep insight. In optics, we present examples of various micro-and nano-optical components, including refractive free-form surfaces, diffractive elements, hybrid diffractive-refractive elements, and multicomponent optical systems. In addition, we describe the fabrication of waveguides and waveguide connections that enable the development of complex photonic circuits in research. In the field of microfluidics, we show how TPP can be used for the development of novel lab-on-a-chip (LOC) systems, including various examples of integrated microfluidic components such as mixers, filters and flow meters, as well as complex optofluidic components such as sensitive refractometers. In the last part of the chapter, we also present interesting biomedical applications, with a particular focus on the production of scaffolds for tissue engineering (TE) and rapid prototyping of medically relevant structures, such as microstructures for transdermal drug delivery or patient-specific implants and prostheses.

AB - Among the additive manufacturing processes, two-photon polymerization (TPP) is one of the most flexible and high-resolution processes of our time, as it enables the production of arbitrary three-dimensional structures on the basis of computer-aided design (CAD) models with a resolution of less than 100 nm. These properties open up new possibilities for the development of novel and miniaturized components for different applications, so that today TPP is successfully used in various areas of research. In this chapter we would like to cover the three largest areas of application of TPP, namely, optics, microfluidics, and biomedicine, and present interesting results that should give the reader a deep insight. In optics, we present examples of various micro-and nano-optical components, including refractive free-form surfaces, diffractive elements, hybrid diffractive-refractive elements, and multicomponent optical systems. In addition, we describe the fabrication of waveguides and waveguide connections that enable the development of complex photonic circuits in research. In the field of microfluidics, we show how TPP can be used for the development of novel lab-on-a-chip (LOC) systems, including various examples of integrated microfluidic components such as mixers, filters and flow meters, as well as complex optofluidic components such as sensitive refractometers. In the last part of the chapter, we also present interesting biomedical applications, with a particular focus on the production of scaffolds for tissue engineering (TE) and rapid prototyping of medically relevant structures, such as microstructures for transdermal drug delivery or patient-specific implants and prostheses.

UR - http://www.scopus.com/inward/record.url?scp=85160123788&partnerID=8YFLogxK

U2 - 10.1007/978-3-030-63647-0_35

DO - 10.1007/978-3-030-63647-0_35

M3 - Contribution to book/anthology

AN - SCOPUS:85160123788

SN - 9783030636463

SP - 1691

EP - 1737

BT - Handbook of Laser Micro-and Nano-Engineering

PB - Springer International Publishing AG

ER -