Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Jacob Friedemann Fast
  • Apurva Muley
  • Daniela Kühn
  • Frederik Meisoll
  • Tobias Ortmaier
  • Michael Jungheim
  • Martin Ptok
  • Lüder Alexander Kahrs

Organisationseinheiten

Externe Organisationen

  • Medizinische Hochschule Hannover (MHH)
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)239-243
Seitenumfang5
FachzeitschriftCurrent Directions in Biomedical Engineering
Jahrgang3
Ausgabenummer2
PublikationsstatusVeröffentlicht - Sept. 2017

Abstract

The so-called Laryngeal Adductor Reflex (LAR) protects the respiratory tract from particle intrusion by quickly approximating the vocal folds to close the free glottal space. An impaired LAR may be associated with an increased risk of aspiration and other adverse conditions. To evaluate the integrity of the LAR, we recently developed an endoscopic prototype for LAR triggering by shooting accelerated droplets onto a predefined laryngeal target region. We now modified the existing droplet-dispensing system to adapt the fluid system pressure as well as the valve opening time to user-chosen values autonomously. This has been accomplished using a microcontroller board connected to a pressure sensor and a mechatronic syringe pump. For performance validation, we designed a measurement setup capable of tracking the droplet along a vertical trajectory. In addition to the experimental setup, the influence of parameters such as system pressure and valve opening time on the micro-droplet formation is presented. Further development will enable the physician to adjust the droplet momentum by setting a single input value on the microcontroller-based setup, thus further increasing usability of the diagnostic device.

ASJC Scopus Sachgebiete

Zitieren

Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering. / Fast, Jacob Friedemann; Muley, Apurva; Kühn, Daniela et al.
in: Current Directions in Biomedical Engineering, Jahrgang 3, Nr. 2, 09.2017, S. 239-243.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Fast, JF, Muley, A, Kühn, D, Meisoll, F, Ortmaier, T, Jungheim, M, Ptok, M & Kahrs, LA 2017, 'Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering', Current Directions in Biomedical Engineering, Jg. 3, Nr. 2, S. 239-243. https://doi.org/10.1515/cdbme-2017-0050
Fast, J. F., Muley, A., Kühn, D., Meisoll, F., Ortmaier, T., Jungheim, M., Ptok, M., & Kahrs, L. A. (2017). Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering. Current Directions in Biomedical Engineering, 3(2), 239-243. https://doi.org/10.1515/cdbme-2017-0050
Fast JF, Muley A, Kühn D, Meisoll F, Ortmaier T, Jungheim M et al. Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering. Current Directions in Biomedical Engineering. 2017 Sep;3(2):239-243. doi: 10.1515/cdbme-2017-0050
Fast, Jacob Friedemann ; Muley, Apurva ; Kühn, Daniela et al. / Towards microprocessor-based control of droplet parameters for endoscopic laryngeal adductor reflex triggering. in: Current Directions in Biomedical Engineering. 2017 ; Jahrgang 3, Nr. 2. S. 239-243.
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abstract = "The so-called Laryngeal Adductor Reflex (LAR) protects the respiratory tract from particle intrusion by quickly approximating the vocal folds to close the free glottal space. An impaired LAR may be associated with an increased risk of aspiration and other adverse conditions. To evaluate the integrity of the LAR, we recently developed an endoscopic prototype for LAR triggering by shooting accelerated droplets onto a predefined laryngeal target region. We now modified the existing droplet-dispensing system to adapt the fluid system pressure as well as the valve opening time to user-chosen values autonomously. This has been accomplished using a microcontroller board connected to a pressure sensor and a mechatronic syringe pump. For performance validation, we designed a measurement setup capable of tracking the droplet along a vertical trajectory. In addition to the experimental setup, the influence of parameters such as system pressure and valve opening time on the micro-droplet formation is presented. Further development will enable the physician to adjust the droplet momentum by setting a single input value on the microcontroller-based setup, thus further increasing usability of the diagnostic device.",
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AU - Fast, Jacob Friedemann

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AU - Kühn, Daniela

AU - Meisoll, Frederik

AU - Ortmaier, Tobias

AU - Jungheim, Michael

AU - Ptok, Martin

AU - Kahrs, Lüder Alexander

N1 - Funding information: Research funding: This research was supported by the German Research Foundation (grants no. KA 2975/6-1 and PT 2/5-1). Conflict of interest: The authors state no conflict of interest. Informed consent: Informed consent is not applicable. Ethical approval: The conducted research was not related to either human or animal trials.

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N2 - The so-called Laryngeal Adductor Reflex (LAR) protects the respiratory tract from particle intrusion by quickly approximating the vocal folds to close the free glottal space. An impaired LAR may be associated with an increased risk of aspiration and other adverse conditions. To evaluate the integrity of the LAR, we recently developed an endoscopic prototype for LAR triggering by shooting accelerated droplets onto a predefined laryngeal target region. We now modified the existing droplet-dispensing system to adapt the fluid system pressure as well as the valve opening time to user-chosen values autonomously. This has been accomplished using a microcontroller board connected to a pressure sensor and a mechatronic syringe pump. For performance validation, we designed a measurement setup capable of tracking the droplet along a vertical trajectory. In addition to the experimental setup, the influence of parameters such as system pressure and valve opening time on the micro-droplet formation is presented. Further development will enable the physician to adjust the droplet momentum by setting a single input value on the microcontroller-based setup, thus further increasing usability of the diagnostic device.

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