The asymmetric vinylogous mukaiyama aldol reaction

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OriginalspracheEnglisch
Seiten (von - bis)173-774
Seitenumfang602
FachzeitschriftOrganic Reactions
Jahrgang98
PublikationsstatusVeröffentlicht - 11 März 2019

Abstract

The vinylogous Mukaiyama aldol (VMA) reaction allows efficient access to larger segments for complex natural product synthesis, primarily polyketides, through the construction of vicinal hydroxyl and methyl groups as well as di- and tri-substituted double bonds in a single operation. In this chapter, the current scope and limitations of this transformation, as well as its application in natural product synthesis, are discussed.

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The asymmetric vinylogous mukaiyama aldol reaction. / Cordes, Martin H. C.; Kalesse, Markus.
in: Organic Reactions, Jahrgang 98, 11.03.2019, S. 173-774.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Cordes MHC, Kalesse M. The asymmetric vinylogous mukaiyama aldol reaction. Organic Reactions. 2019 Mär 11;98:173-774. doi: 10.1002/0471264180.or098.02
Cordes, Martin H. C. ; Kalesse, Markus. / The asymmetric vinylogous mukaiyama aldol reaction. in: Organic Reactions. 2019 ; Jahrgang 98. S. 173-774.
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