Details
| Titel in Übersetzung | Human Papilloma Virus (HPV) Testing for Cervical Carcinoma Screening |
|---|---|
| Originalsprache | Mehrere Sprachen |
| Seiten (von - bis) | 138-142 |
| Seitenumfang | 5 |
| Fachzeitschrift | Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen |
| Jahrgang | 104 |
| Ausgabenummer | 2 |
| Frühes Online-Datum | 30 Juli 2008 |
| Publikationsstatus | Veröffentlicht - 2010 |
Abstract
Cytology-based screening for cervical cancer has been criticised because of its high percentage of false-negative results. Considering HPV testing as an integral part of the screening process has been discussed as a way to address this issue in Germany. The aim of our study was to review trials comparing HPV testing with cytology in cervical cancer screening. Based on a systematic literature review, 14 studies with 85, 820 women could be included. Generally HPV testing was more sensitive, but less specific than cytology. Based on the pooled data, sensitivity and specificity for HPV testing were 91 % and 90%, respectively, whereas sensitivity and specificity for cytology amounted to 66% and 96%, respectively. Based on these results, including HPV testing in primary cervical cancer screening might lead to a reduction of false-negative results. Due the lower specificity false-positive test results would increase though.
Schlagwörter
- Cervical cancer, Cytology, HPV, Human papilloma virus, Screening, Test criteria
ASJC Scopus Sachgebiete
- Medizin (insg.)
- Medizin (sonstige)
- Sozialwissenschaften (insg.)
- Ausbildung bzw. Denomination
- Medizin (insg.)
- Health policy
Ziele für nachhaltige Entwicklung
Zitieren
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- BibTex
- RIS
in: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, Jahrgang 104, Nr. 2, 2010, S. 138-142.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung
AU - Nocon, Marc
AU - Roll, Stephanie
AU - Mittendorf, Thomas
AU - Von der Schulenburg, J. Matthias
AU - Willich, Stefan N.
PY - 2010
Y1 - 2010
N2 - Cytology-based screening for cervical cancer has been criticised because of its high percentage of false-negative results. Considering HPV testing as an integral part of the screening process has been discussed as a way to address this issue in Germany. The aim of our study was to review trials comparing HPV testing with cytology in cervical cancer screening. Based on a systematic literature review, 14 studies with 85, 820 women could be included. Generally HPV testing was more sensitive, but less specific than cytology. Based on the pooled data, sensitivity and specificity for HPV testing were 91 % and 90%, respectively, whereas sensitivity and specificity for cytology amounted to 66% and 96%, respectively. Based on these results, including HPV testing in primary cervical cancer screening might lead to a reduction of false-negative results. Due the lower specificity false-positive test results would increase though.
AB - Cytology-based screening for cervical cancer has been criticised because of its high percentage of false-negative results. Considering HPV testing as an integral part of the screening process has been discussed as a way to address this issue in Germany. The aim of our study was to review trials comparing HPV testing with cytology in cervical cancer screening. Based on a systematic literature review, 14 studies with 85, 820 women could be included. Generally HPV testing was more sensitive, but less specific than cytology. Based on the pooled data, sensitivity and specificity for HPV testing were 91 % and 90%, respectively, whereas sensitivity and specificity for cytology amounted to 66% and 96%, respectively. Based on these results, including HPV testing in primary cervical cancer screening might lead to a reduction of false-negative results. Due the lower specificity false-positive test results would increase though.
KW - Cervical cancer
KW - Cytology
KW - HPV
KW - Human papilloma virus
KW - Screening
KW - Test criteria
UR - http://www.scopus.com/inward/record.url?scp=77952275933&partnerID=8YFLogxK
U2 - 10.1016/j.zefq.2008.06.018
DO - 10.1016/j.zefq.2008.06.018
M3 - Article
C2 - 20441022
AN - SCOPUS:77952275933
VL - 104
SP - 138
EP - 142
JO - Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen
JF - Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen
SN - 1865-9217
IS - 2
ER -