Details
Originalsprache | Englisch |
---|---|
Seiten (von - bis) | 1263-1265 |
Seitenumfang | 3 |
Fachzeitschrift | Tetrahedron letters |
Jahrgang | 42 |
Ausgabenummer | 7 |
Publikationsstatus | Veröffentlicht - 12 Feb. 2001 |
Abstract
Natural products like ratjadone and callystatin A contain an α,β-unsaturated lactone moiety which adds to the biological activity of these compounds. Here we report a rapid and practical access to lactone precursor 3 by an asymmetric hetero Diels-Alder reaction as the key step and its subsequent transformation into a suitable building block 4.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron letters, Jahrgang 42, Nr. 7, 12.02.2001, S. 1263-1265.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Synthesis of unsaturated lactone moieties by asymmetric hetero Diels-Alder reactions with binaphthol-titanium complexes
AU - Quitschalle, Monika
AU - Christmann, Mathias
AU - Bhatt, Ulhas
AU - Kalesse, Markus
PY - 2001/2/12
Y1 - 2001/2/12
N2 - Natural products like ratjadone and callystatin A contain an α,β-unsaturated lactone moiety which adds to the biological activity of these compounds. Here we report a rapid and practical access to lactone precursor 3 by an asymmetric hetero Diels-Alder reaction as the key step and its subsequent transformation into a suitable building block 4.
AB - Natural products like ratjadone and callystatin A contain an α,β-unsaturated lactone moiety which adds to the biological activity of these compounds. Here we report a rapid and practical access to lactone precursor 3 by an asymmetric hetero Diels-Alder reaction as the key step and its subsequent transformation into a suitable building block 4.
UR - http://www.scopus.com/inward/record.url?scp=0035847483&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(00)02213-9
DO - 10.1016/S0040-4039(00)02213-9
M3 - Article
AN - SCOPUS:0035847483
VL - 42
SP - 1263
EP - 1265
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 7
ER -