Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 3553-3556 |
| Seitenumfang | 4 |
| Fachzeitschrift | Tetrahedron letters |
| Jahrgang | 40 |
| Ausgabenummer | 18 |
| Publikationsstatus | Veröffentlicht - 30 Apr. 1999 |
Abstract
The synthesis of the strained epothilone analog containing a ten- membered ring as well as the northern hemisphere of epothilone A is described. This approach, using the ring closing metathesis reaction, is a solution to the lack of stereocontrol observed in the ring closing metathesis reaction utilized in the synthesis of the epothilone backbone by other groups.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Tetrahedron letters, Jahrgang 40, Nr. 18, 30.04.1999, S. 3553-3556.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Synthesis of the northern hemisphere of epothilone A by a ten-membered ring closing metathesis reaction
AU - Gerlach, Kai
AU - Quitschalle, Monika
AU - Kalesse, Markus
PY - 1999/4/30
Y1 - 1999/4/30
N2 - The synthesis of the strained epothilone analog containing a ten- membered ring as well as the northern hemisphere of epothilone A is described. This approach, using the ring closing metathesis reaction, is a solution to the lack of stereocontrol observed in the ring closing metathesis reaction utilized in the synthesis of the epothilone backbone by other groups.
AB - The synthesis of the strained epothilone analog containing a ten- membered ring as well as the northern hemisphere of epothilone A is described. This approach, using the ring closing metathesis reaction, is a solution to the lack of stereocontrol observed in the ring closing metathesis reaction utilized in the synthesis of the epothilone backbone by other groups.
UR - http://www.scopus.com/inward/record.url?scp=0033617388&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(99)00550-X
DO - 10.1016/S0040-4039(99)00550-X
M3 - Article
AN - SCOPUS:0033617388
VL - 40
SP - 3553
EP - 3556
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 18
ER -