Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 245-256 |
| Seitenumfang | 12 |
| Fachzeitschrift | Carbohydrate Research |
| Jahrgang | 256 |
| Ausgabenummer | 2 |
| Publikationsstatus | Veröffentlicht - 1 Apr. 1994 |
| Extern publiziert | Ja |
Abstract
The synthesis of 4-amino-3,4-dideoxy-d-arabino-heptulosonic acid 7-phosphate (15), the first committed intermediate in a new branch of the shikimate pathway of aromatic biosynthesis, is reported from 2-deoxy-d-glucose in 14 steps in 10-12% overall yield.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Analytische Chemie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Chemie (insg.)
- Organische Chemie
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in: Carbohydrate Research, Jahrgang 256, Nr. 2, 01.04.1994, S. 245-256.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Synthesis of 4-amino 3,4-dideoxy-d-arabino-heptulosonic acid 7-phosphate, the biosynthetic precursor of C7N units in ansamycin antibiotics
AU - Kirschning, Andreas
AU - Bergon, Philippe
AU - Wang, Jeh Jeng
AU - Breazeale, Steven
AU - Floss, Heinz G.
N1 - Funding information: This work was supportedb y the National Institutes of Health through research grant AI 20264a nd by the Alexander von Humboldt Foundation, Bad Godesberg, through a Lynen Postdoctoral Fellowship to A.K.
PY - 1994/4/1
Y1 - 1994/4/1
N2 - The synthesis of 4-amino-3,4-dideoxy-d-arabino-heptulosonic acid 7-phosphate (15), the first committed intermediate in a new branch of the shikimate pathway of aromatic biosynthesis, is reported from 2-deoxy-d-glucose in 14 steps in 10-12% overall yield.
AB - The synthesis of 4-amino-3,4-dideoxy-d-arabino-heptulosonic acid 7-phosphate (15), the first committed intermediate in a new branch of the shikimate pathway of aromatic biosynthesis, is reported from 2-deoxy-d-glucose in 14 steps in 10-12% overall yield.
UR - http://www.scopus.com/inward/record.url?scp=0028413961&partnerID=8YFLogxK
U2 - 10.1016/0008-6215(94)84211-6
DO - 10.1016/0008-6215(94)84211-6
M3 - Article
C2 - 8187101
AN - SCOPUS:0028413961
VL - 256
SP - 245
EP - 256
JO - Carbohydrate Research
JF - Carbohydrate Research
SN - 0008-6215
IS - 2
ER -