Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 253-257 |
| Seitenumfang | 5 |
| Fachzeitschrift | CHEMBIOCHEM |
| Jahrgang | 3 |
| Ausgabenummer | 2-3 |
| Publikationsstatus | Veröffentlicht - 1 März 2002 |
| Extern publiziert | Ja |
Abstract
β-oxoacyl thiolesters of N-acetylcysteamine (SNACs, see structure) were synthesised and shown to be substrates for the self-acylation reaction of the Type II actinorhodin polyketide synthase holo acyl carrier protein (ACP). The preparation of ACPs bearing analogues of polyketide biosynthesis intermediates is described.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Molekularmedizin
- Biochemie, Genetik und Molekularbiologie (insg.)
- Molekularbiologie
- Chemie (insg.)
- Organische Chemie
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in: CHEMBIOCHEM, Jahrgang 3, Nr. 2-3, 01.03.2002, S. 253-257.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Synthesis and characterisation of acyl carrier protein bound polyketide analogues
AU - Arthur, Christopher
AU - Cox, Russell J.
AU - Crosby, John
AU - Rahman, Mujiber M.
AU - Simpson, Thomas J.
AU - Soulas, Florilene
AU - Spogli, Roberto
AU - Szafranska, Anna E.
AU - Westcott, James
AU - Winfield, Christopher J.
PY - 2002/3/1
Y1 - 2002/3/1
N2 - β-oxoacyl thiolesters of N-acetylcysteamine (SNACs, see structure) were synthesised and shown to be substrates for the self-acylation reaction of the Type II actinorhodin polyketide synthase holo acyl carrier protein (ACP). The preparation of ACPs bearing analogues of polyketide biosynthesis intermediates is described.
AB - β-oxoacyl thiolesters of N-acetylcysteamine (SNACs, see structure) were synthesised and shown to be substrates for the self-acylation reaction of the Type II actinorhodin polyketide synthase holo acyl carrier protein (ACP). The preparation of ACPs bearing analogues of polyketide biosynthesis intermediates is described.
KW - Acyl carrier protein
KW - Biosynthesis
KW - Intermediates
KW - Polyketides
UR - http://www.scopus.com/inward/record.url?scp=0036523469&partnerID=8YFLogxK
U2 - 10.1002/1439-7633(20020301)3:2/3<253::AID-CBIC253>3.0.CO;2-7
DO - 10.1002/1439-7633(20020301)3:2/3<253::AID-CBIC253>3.0.CO;2-7
M3 - Article
C2 - 11921408
AN - SCOPUS:0036523469
VL - 3
SP - 253
EP - 257
JO - CHEMBIOCHEM
JF - CHEMBIOCHEM
SN - 1439-4227
IS - 2-3
ER -