Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents

K. C. Nicolaou; Min Lu; Sotirios Totokotsopoulos; Philipp Heretsch; Denis Giguere; Ya-Ping Sun; David Sarlah; Thu H. Nguyen; Ian C. Wolf; Donald F. Smee; Craig W. Day; Selina Bopp; Elizabeth A. Winzeler

doi:10.1021/ja308429f

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Originalsprache	Englisch
Seiten (von - bis)	17320-17332
Fachzeitschrift	Journal of the American Chemical Society
Jahrgang	134
Ausgabenummer	41
Publikationsstatus	Veröffentlicht - 17 Okt. 2012

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Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents. / Nicolaou, K. C.; Lu, Min; Totokotsopoulos, Sotirios et al.
in: Journal of the American Chemical Society, Jahrgang 134, Nr. 41, 17.10.2012, S. 17320-17332.

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Nicolaou, KC, Lu, M, Totokotsopoulos, S, Heretsch, P, Giguere, D, Sun, Y-P, Sarlah, D, Nguyen, TH, Wolf, IC, Smee, DF, Day, CW, Bopp, S & Winzeler, EA 2012, 'Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents', Journal of the American Chemical Society, Jg. 134, Nr. 41, S. 17320-17332. https://doi.org/10.1021/ja308429f

Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y.-P., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S., & Winzeler, E. A. (2012). Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents. Journal of the American Chemical Society, 134(41), 17320-17332. https://doi.org/10.1021/ja308429f

Nicolaou KC, Lu M, Totokotsopoulos S, Heretsch P, Giguere D, Sun YP et al. Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents. Journal of the American Chemical Society. 2012 Okt 17;134(41):17320-17332. doi: 10.1021/ja308429f

Nicolaou, K. C. ; Lu, Min ; Totokotsopoulos, Sotirios et al. / Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents. in: Journal of the American Chemical Society. 2012 ; Jahrgang 134, Nr. 41. S. 17320-17332.

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title = "Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents",

author = "Nicolaou, {K. C.} and Min Lu and Sotirios Totokotsopoulos and Philipp Heretsch and Denis Giguere and Ya-Ping Sun and David Sarlah and Nguyen, {Thu H.} and Wolf, {Ian C.} and Smee, {Donald F.} and Day, {Craig W.} and Selina Bopp and Winzeler, {Elizabeth A.}",

year = "2012",

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language = "English",

volume = "134",

pages = "17320--17332",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents

AU - Nicolaou, K. C.

AU - Lu, Min

AU - Totokotsopoulos, Sotirios

AU - Heretsch, Philipp

AU - Giguere, Denis

AU - Sun, Ya-Ping

AU - Sarlah, David

AU - Nguyen, Thu H.

AU - Wolf, Ian C.

AU - Smee, Donald F.

AU - Day, Craig W.

AU - Bopp, Selina

AU - Winzeler, Elizabeth A.

PY - 2012/10/17

Y1 - 2012/10/17

U2 - 10.1021/ja308429f

DO - 10.1021/ja308429f

M3 - Article

VL - 134

SP - 17320

EP - 17332

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 41

ER -

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