Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 1235-1240 |
| Seitenumfang | 6 |
| Fachzeitschrift | Journal of natural products |
| Jahrgang | 80 |
| Ausgabenummer | 5 |
| Publikationsstatus | Veröffentlicht - 26 Mai 2017 |
Abstract
The structure of the fungal phytotoxins known as the phyllostictines has been revised to a series of bicyclic 3-methylene tetramic acids. Genome sequencing of the producing organism Phyllostica cirsii has revealed a biosynthetic gene cluster responsible for the biosynthesis of the phyllostictines, and targeted knockout experiments have proven the link and produced an intermediate.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Analytische Chemie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Molekularmedizin
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Pharmakologie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Pharmazeutische Wissenschaften
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Medizin (insg.)
- Ergänzende und alternative Medizin
- Chemie (insg.)
- Organische Chemie
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in: Journal of natural products, Jahrgang 80, Nr. 5, 26.05.2017, S. 1235-1240.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Structural Revision and Biosynthesis of the Fungal Phytotoxins Phyllostictines A and B
AU - Trenti, Francesco
AU - Cox, Russell J.
PY - 2017/5/26
Y1 - 2017/5/26
N2 - The structure of the fungal phytotoxins known as the phyllostictines has been revised to a series of bicyclic 3-methylene tetramic acids. Genome sequencing of the producing organism Phyllostica cirsii has revealed a biosynthetic gene cluster responsible for the biosynthesis of the phyllostictines, and targeted knockout experiments have proven the link and produced an intermediate.
AB - The structure of the fungal phytotoxins known as the phyllostictines has been revised to a series of bicyclic 3-methylene tetramic acids. Genome sequencing of the producing organism Phyllostica cirsii has revealed a biosynthetic gene cluster responsible for the biosynthesis of the phyllostictines, and targeted knockout experiments have proven the link and produced an intermediate.
UR - http://www.scopus.com/inward/record.url?scp=85019715951&partnerID=8YFLogxK
U2 - 10.1021/acs.jnatprod.7b00183
DO - 10.1021/acs.jnatprod.7b00183
M3 - Article
C2 - 28467083
AN - SCOPUS:85019715951
VL - 80
SP - 1235
EP - 1240
JO - Journal of natural products
JF - Journal of natural products
SN - 0163-3864
IS - 5
ER -