Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 1919-1929 |
| Seitenumfang | 11 |
| Fachzeitschrift | Organic and Biomolecular Chemistry |
| Jahrgang | 1 |
| Ausgabenummer | 11 |
| Frühes Online-Datum | 30 Apr. 2003 |
| Publikationsstatus | Veröffentlicht - 2003 |
| Extern publiziert | Ja |
Abstract
A practical route is described for the preparation of azido-myo-inositols, amino-myo-inositols and azido-conduritol B derivatives. Starting from p-benzoquinone, optically pure compounds in both forms can be prepared via enzymatic resolution of a derived diacetoxy conduritol B derivative. Selective introduction of nitrogen-containing functional groups in four of the six possible positions in the cyclitol moiety is followed by further functionalization to yield the target compounds.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Chemie (insg.)
- Physikalische und Theoretische Chemie
- Chemie (insg.)
- Organische Chemie
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in: Organic and Biomolecular Chemistry, Jahrgang 1, Nr. 11, 2003, S. 1919-1929.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Stereoselective synthesis of several azido/amino- and diazido/diamino-myo-inositols and their phosphates from p-benzoquinone
AU - Podeschwa, Michael A.L.
AU - Plettenburg, Oliver
AU - Altenbach, Hans Josef
N1 - Funding Information: We are grateful to the Bayer AG Company for supporting this project in many aspects, especially for preparing the HR-MS spectra. We also thank in particular Dr. W. Schrader and Mrs. Blumenthal (Max-Planck Institut für Kohlenforschung) for mass spectra analysis. We thank Dr S. Adelt and G. Dallmann for purification of the inositol phosphates.
PY - 2003
Y1 - 2003
N2 - A practical route is described for the preparation of azido-myo-inositols, amino-myo-inositols and azido-conduritol B derivatives. Starting from p-benzoquinone, optically pure compounds in both forms can be prepared via enzymatic resolution of a derived diacetoxy conduritol B derivative. Selective introduction of nitrogen-containing functional groups in four of the six possible positions in the cyclitol moiety is followed by further functionalization to yield the target compounds.
AB - A practical route is described for the preparation of azido-myo-inositols, amino-myo-inositols and azido-conduritol B derivatives. Starting from p-benzoquinone, optically pure compounds in both forms can be prepared via enzymatic resolution of a derived diacetoxy conduritol B derivative. Selective introduction of nitrogen-containing functional groups in four of the six possible positions in the cyclitol moiety is followed by further functionalization to yield the target compounds.
UR - http://www.scopus.com/inward/record.url?scp=0037588943&partnerID=8YFLogxK
U2 - 10.1039/b302622a
DO - 10.1039/b302622a
M3 - Article
C2 - 12945774
AN - SCOPUS:0037588943
VL - 1
SP - 1919
EP - 1929
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 11
ER -