Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays

Publikation: Beitrag in Fachzeitschrift › Übersichtsarbeit › Forschung › Peer-Review

Autoren

  • Frank Bretz
  • Ludwig A. Hothorn

Organisationseinheiten

Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)81-96
Seitenumfang16
FachzeitschriftAlternatives to laboratory animals
Jahrgang31
AusgabenummerSUPPL. 1
PublikationsstatusVeröffentlicht - Nov. 2003

Abstract

Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.

ASJC Scopus Sachgebiete

Zitieren

Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays. / Bretz, Frank; Hothorn, Ludwig A.
in: Alternatives to laboratory animals, Jahrgang 31, Nr. SUPPL. 1, 11.2003, S. 81-96.

Publikation: Beitrag in Fachzeitschrift › Übersichtsarbeit › Forschung › Peer-Review

Download
@article{172858eb73f94386a4a8886561acd4ec,
title = "Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays",
abstract = "Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.",
keywords = "Contrast test, Dose-response analysis, In vitro toxicological assay, Non-monotone, Trend test",
author = "Frank Bretz and Hothorn, {Ludwig A.}",
year = "2003",
month = nov,
doi = "10.1177/026119290303101s06",
language = "English",
volume = "31",
pages = "81--96",
journal = "Alternatives to laboratory animals",
issn = "0261-1929",
publisher = "FRAME",
number = "SUPPL. 1",

}

Download

TY - JOUR

T1 - Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays

AU - Bretz, Frank

AU - Hothorn, Ludwig A.

PY - 2003/11

Y1 - 2003/11

N2 - Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.

AB - Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.

KW - Contrast test

KW - Dose-response analysis

KW - In vitro toxicological assay

KW - Non-monotone

KW - Trend test

UR - http://www.scopus.com/inward/record.url?scp=0042697233&partnerID=8YFLogxK

U2 - 10.1177/026119290303101s06

DO - 10.1177/026119290303101s06

M3 - Review article

C2 - 15595903

AN - SCOPUS:0042697233

VL - 31

SP - 81

EP - 96

JO - Alternatives to laboratory animals

JF - Alternatives to laboratory animals

SN - 0261-1929

IS - SUPPL. 1

ER -