Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 2257-2270 |
| Seitenumfang | 14 |
| Fachzeitschrift | Journal of Adhesion Science and Technology |
| Jahrgang | 24 |
| Ausgabenummer | 13-14 |
| Publikationsstatus | Veröffentlicht - 1 Sept. 2010 |
| Extern publiziert | Ja |
Abstract
In this work we present an in vitro study of the influence of two types of femtosecond laser generated topographies on a titanium surface - grooves with different periodicities and "lotus-like" structures - on the behavior of human fibroblast and MG-63 osteoblast cells. We show that anisotropy in wetting of groove structures correlates well with contact guidance of cells. The "lotus-like" structured titanium surfaces show superhydrophobic properties and influence differentially osteoblast and fibroblast adhesion and growth. The proliferation of fibroblast cells is inhibited, whereas the proliferation of osteoblast cells is promoted. This technique for cell specific control offers promising perspectives in fabrication of new functionalized implants.
ASJC Scopus Sachgebiete
- Chemie (insg.)
- Allgemeine Chemie
- Ingenieurwesen (insg.)
- Werkstoffmechanik
- Physik und Astronomie (insg.)
- Oberflächen und Grenzflächen
- Werkstoffwissenschaften (insg.)
- Oberflächen, Beschichtungen und Folien
- Werkstoffwissenschaften (insg.)
- Werkstoffchemie
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in: Journal of Adhesion Science and Technology, Jahrgang 24, Nr. 13-14, 01.09.2010, S. 2257-2270.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Selective Cell Control by Surface Structuring for Orthopedic Applications
AU - Fadeeva, E.
AU - Schlie, S.
AU - Koch, J.
AU - Chichkov, B. N.
N1 - Funding information: This work was supported by the German Research Foundation, DFG, under the projects SFB599 “Sustaintable Bioresorbing and Permanent Implants of Metallic and Ceramic Materials” and Transregio Project TR37.
PY - 2010/9/1
Y1 - 2010/9/1
N2 - In this work we present an in vitro study of the influence of two types of femtosecond laser generated topographies on a titanium surface - grooves with different periodicities and "lotus-like" structures - on the behavior of human fibroblast and MG-63 osteoblast cells. We show that anisotropy in wetting of groove structures correlates well with contact guidance of cells. The "lotus-like" structured titanium surfaces show superhydrophobic properties and influence differentially osteoblast and fibroblast adhesion and growth. The proliferation of fibroblast cells is inhibited, whereas the proliferation of osteoblast cells is promoted. This technique for cell specific control offers promising perspectives in fabrication of new functionalized implants.
AB - In this work we present an in vitro study of the influence of two types of femtosecond laser generated topographies on a titanium surface - grooves with different periodicities and "lotus-like" structures - on the behavior of human fibroblast and MG-63 osteoblast cells. We show that anisotropy in wetting of groove structures correlates well with contact guidance of cells. The "lotus-like" structured titanium surfaces show superhydrophobic properties and influence differentially osteoblast and fibroblast adhesion and growth. The proliferation of fibroblast cells is inhibited, whereas the proliferation of osteoblast cells is promoted. This technique for cell specific control offers promising perspectives in fabrication of new functionalized implants.
KW - contact angle
KW - Femtosecond laser fabrication
KW - fibroblast
KW - osteoblast
KW - surface topography
KW - titanium
UR - http://www.scopus.com/inward/record.url?scp=77957574068&partnerID=8YFLogxK
U2 - 10.1163/016942410X508000
DO - 10.1163/016942410X508000
M3 - Article
AN - SCOPUS:77957574068
VL - 24
SP - 2257
EP - 2270
JO - Journal of Adhesion Science and Technology
JF - Journal of Adhesion Science and Technology
SN - 0169-4243
IS - 13-14
ER -