TY - JOUR

T1 - Role of Sonification and Rhythmic Auditory Cueing for Enhancing Gait Associated Deficits Induced by Neurotoxic Cancer Therapies

T2 - A Perspective on Auditory Neuroprosthetics

AU - Ghai, Shashank

AU - Ghai, Ishan

N1 - Funding Information: The publication of this article was funded by the Open Access fund of Leibniz Universität Hannover.

PY - 2019/1/29

Y1 - 2019/1/29

N2 - Patients undergoing chemotherapy, radiotherapy, and immunotherapy experience neurotoxic changes in the central and peripheral nervous system. These neurotoxic changes adversely affect functioning in the sensory, motor, and cognitive domains. Thereby, considerably affecting autonomic activities like gait and posture. Recent evidence from a range of systematic reviews and meta-analyses have suggested the beneficial influence of music-based external auditory stimulations i.e., rhythmic auditory cueing and real-time auditory feedback (sonification) on gait and postural stability in population groups will balance disorders. This perspective explores the conjunct implications of auditory stimulations during cancer treatment to simultaneously reduce gait and posture related deficits. Underlying neurophysiological mechanisms by which auditory stimulations might influence motor performance have been discussed. Prompt recognition of this sensorimotor training strategy in future studies can have a widespread impact on patient care in all areas of oncology.

AB - Patients undergoing chemotherapy, radiotherapy, and immunotherapy experience neurotoxic changes in the central and peripheral nervous system. These neurotoxic changes adversely affect functioning in the sensory, motor, and cognitive domains. Thereby, considerably affecting autonomic activities like gait and posture. Recent evidence from a range of systematic reviews and meta-analyses have suggested the beneficial influence of music-based external auditory stimulations i.e., rhythmic auditory cueing and real-time auditory feedback (sonification) on gait and postural stability in population groups will balance disorders. This perspective explores the conjunct implications of auditory stimulations during cancer treatment to simultaneously reduce gait and posture related deficits. Underlying neurophysiological mechanisms by which auditory stimulations might influence motor performance have been discussed. Prompt recognition of this sensorimotor training strategy in future studies can have a widespread impact on patient care in all areas of oncology.

KW - Balance

KW - Chemotherapy

KW - Cueing

KW - Perception

KW - Performance

KW - Rehabilitation

KW - Stability

UR - http://www.scopus.com/inward/record.url?scp=85061749386&partnerID=8YFLogxK

U2 - 10.3389/fneur.2019.00021

DO - 10.3389/fneur.2019.00021

M3 - Article

AN - SCOPUS:85061749386

VL - 10

JO - Frontiers in neurology

JF - Frontiers in neurology

SN - 1664-2295

IS - JAN

M1 - 21

ER -