Raspberry ketone from submerged cultured cells of the basidiomycete Nidula niveo-tomentosa

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Andreas Böker
  • R. G. Berger
  • Manuela Fischer

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OriginalspracheEnglisch
Seiten (von - bis)568-572
Seitenumfang5
FachzeitschriftBiotechnology progress
Jahrgang17
Ausgabenummer3
PublikationsstatusVeröffentlicht - 2001

Abstract

The basidiomycete Nidula niveo-tomentosa produced 4-(4-hydroxyphenyl)-butan-2-one (raspberry ketone), one of the character impact components of raspberry flavor, and its corresponding alcohol. A systematic attempt was made to improve the productivity of this fungus. Variation of nutrient medium composition, precursor amount, time of supplementation, and cultivation period yielded a 50-fold increase in metabolite concentrations. Raspberry ketone and alcohol were easily isolated from the culture medium by solvent extraction. Glycosidically bound forms or accumulation of raspberry compounds in fungal cells were not detected. This microbial process offers an alternative for the production of natural raspberry flavor.

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Raspberry ketone from submerged cultured cells of the basidiomycete Nidula niveo-tomentosa. / Böker, Andreas; Berger, R. G.; Fischer, Manuela.
in: Biotechnology progress, Jahrgang 17, Nr. 3, 2001, S. 568-572.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Böker A, Berger RG, Fischer M. Raspberry ketone from submerged cultured cells of the basidiomycete Nidula niveo-tomentosa. Biotechnology progress. 2001;17(3):568-572. doi: 10.1021/bp010011b
Böker, Andreas ; Berger, R. G. ; Fischer, Manuela. / Raspberry ketone from submerged cultured cells of the basidiomycete Nidula niveo-tomentosa. in: Biotechnology progress. 2001 ; Jahrgang 17, Nr. 3. S. 568-572.
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