Rapid Prototyping of Biomimetic Structures: Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Autoren

  • Shaun D. Gittard
  • Roger J. Narayan
  • Aleksandr Ovsianikov
  • Boris N. Chichkov

Externe Organisationen

  • North Carolina State University
  • Laser Zentrum Hannover e.V. (LZH)
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Titel des SammelwerksMicro- and Nanoscale Processing of Biomaterials
Seiten31-39
Seitenumfang9
PublikationsstatusVeröffentlicht - 2010
Extern publiziertJa
Veranstaltung2009 MRS Fall Meeting - Boston, USA / Vereinigte Staaten
Dauer: 30 Nov. 20094 Dez. 2009

Publikationsreihe

NameMaterials Research Society Symposium Proceedings
Band1239
ISSN (Print)0272-9172

Abstract

Over the past twenty years, the use of rapid prototyping techniques for processing of medical devices has seen rapid growth. A number of rapid prototyping techniques currently exist for producing a broad range of medical devices using metals, ceramics, polymers, and composite materials. One promising rapid prototyping technology for creating medical devices with small scale features is two photon polymerization; this scalable photopolymerization technique enables processing of photosensitive materials such as organically-modified ceramic materials. In this study, two photon polymerization was used to produce microneedles that mimic the anatomy of the mosquito fascicle. The labrum of the mosquito was replicated in the mosquito-like microneedle. On the other hand, the maxillae of the mosquito were not replicated in the mosquito-like microneedle; the absence of these features was attributed to inadequate mechanical support of the maxillae. This study suggests that two photon polymerization and other rapid prototyping technologies may be used to produce biomimetic drug delivery devices that imitate the intricate structures found in nature.

ASJC Scopus Sachgebiete

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Rapid Prototyping of Biomimetic Structures: Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization. / Gittard, Shaun D.; Narayan, Roger J.; Ovsianikov, Aleksandr et al.
Micro- and Nanoscale Processing of Biomaterials. 2010. S. 31-39 (Materials Research Society Symposium Proceedings; Band 1239).

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Gittard, SD, Narayan, RJ, Ovsianikov, A & Chichkov, BN 2010, Rapid Prototyping of Biomimetic Structures: Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization. in Micro- and Nanoscale Processing of Biomaterials. Materials Research Society Symposium Proceedings, Bd. 1239, S. 31-39, 2009 MRS Fall Meeting, Boston, Massachusetts, USA / Vereinigte Staaten, 30 Nov. 2009. https://doi.org/10.1557/PROC-1239-VV01-11
Gittard, S. D., Narayan, R. J., Ovsianikov, A., & Chichkov, B. N. (2010). Rapid Prototyping of Biomimetic Structures: Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization. In Micro- and Nanoscale Processing of Biomaterials (S. 31-39). (Materials Research Society Symposium Proceedings; Band 1239). https://doi.org/10.1557/PROC-1239-VV01-11
Gittard SD, Narayan RJ, Ovsianikov A, Chichkov BN. Rapid Prototyping of Biomimetic Structures: Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization. in Micro- and Nanoscale Processing of Biomaterials. 2010. S. 31-39. (Materials Research Society Symposium Proceedings). doi: 10.1557/PROC-1239-VV01-11
Gittard, Shaun D. ; Narayan, Roger J. ; Ovsianikov, Aleksandr et al. / Rapid Prototyping of Biomimetic Structures : Fabrication of Mosquito-Like Microneedles by Two-Photon Polymerization. Micro- and Nanoscale Processing of Biomaterials. 2010. S. 31-39 (Materials Research Society Symposium Proceedings).
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