Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 2260-2261 |
| Seitenumfang | 2 |
| Fachzeitschrift | Chemical communications |
| Ausgabenummer | 20 |
| Publikationsstatus | Veröffentlicht - 21 Okt. 2004 |
| Extern publiziert | Ja |
Abstract
PCR primers designed to selectively amplify the unique C-methyltransferase domain of fungal polyketide synthases were used to selectively clone a polyketide synthase gene involved in the biosynthesis of the squalene synthase inhibitor squalestatin S1 1, heterologous expression of which led to the biosynthesis of the squalestatin side-chain.
ASJC Scopus Sachgebiete
- Chemische Verfahrenstechnik (insg.)
- Katalyse
- Werkstoffwissenschaften (insg.)
- Elektronische, optische und magnetische Materialien
- Werkstoffwissenschaften (insg.)
- Keramische und Verbundwerkstoffe
- Chemie (insg.)
- Allgemeine Chemie
- Werkstoffwissenschaften (insg.)
- Oberflächen, Beschichtungen und Folien
- Werkstoffwissenschaften (insg.)
- Metalle und Legierungen
- Werkstoffwissenschaften (insg.)
- Werkstoffchemie
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in: Chemical communications, Nr. 20, 21.10.2004, S. 2260-2261.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis
AU - Cox, Russell J.
AU - Glod, Frank
AU - Hurley, Deirdre
AU - Lazarus, Colin M.
AU - Nicholson, Thomas P.
AU - Rudd, Brian A.M.
AU - Simpson, Thomas J.
AU - Wilkinson, Barrie
AU - Zhang, Ying
PY - 2004/10/21
Y1 - 2004/10/21
N2 - PCR primers designed to selectively amplify the unique C-methyltransferase domain of fungal polyketide synthases were used to selectively clone a polyketide synthase gene involved in the biosynthesis of the squalene synthase inhibitor squalestatin S1 1, heterologous expression of which led to the biosynthesis of the squalestatin side-chain.
AB - PCR primers designed to selectively amplify the unique C-methyltransferase domain of fungal polyketide synthases were used to selectively clone a polyketide synthase gene involved in the biosynthesis of the squalene synthase inhibitor squalestatin S1 1, heterologous expression of which led to the biosynthesis of the squalestatin side-chain.
UR - http://www.scopus.com/inward/record.url?scp=9144262560&partnerID=8YFLogxK
U2 - 10.1039/b411973h
DO - 10.1039/b411973h
M3 - Article
C2 - 15489970
AN - SCOPUS:9144262560
SP - 2260
EP - 2261
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 20
ER -