Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 3561-3564 |
| Seitenumfang | 4 |
| Fachzeitschrift | Organic letters |
| Jahrgang | 3 |
| Ausgabenummer | 22 |
| Publikationsstatus | Veröffentlicht - 1 Nov. 2001 |
Abstract
(matrix presented) The use of the Z-configured vinylogous silyl ketene acetals in Mukaiyama aldol reactions is described, Isopropyl alcohol as scavanger and the use of tris(pentafluorophenyl)borane as the Lewis acid are required for obtaining the γ-alkylated syn-product selectively. In cases of α-chiral aldehydes, Felkin-Anh selectivity was observed.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Chemie (insg.)
- Physikalische und Theoretische Chemie
- Chemie (insg.)
- Organische Chemie
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in: Organic letters, Jahrgang 3, Nr. 22, 01.11.2001, S. 3561-3564.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions
AU - Hassfeld, Jorma
AU - Christmann, Mathias
AU - Kalesse, Markus
PY - 2001/11/1
Y1 - 2001/11/1
N2 - (matrix presented) The use of the Z-configured vinylogous silyl ketene acetals in Mukaiyama aldol reactions is described, Isopropyl alcohol as scavanger and the use of tris(pentafluorophenyl)borane as the Lewis acid are required for obtaining the γ-alkylated syn-product selectively. In cases of α-chiral aldehydes, Felkin-Anh selectivity was observed.
AB - (matrix presented) The use of the Z-configured vinylogous silyl ketene acetals in Mukaiyama aldol reactions is described, Isopropyl alcohol as scavanger and the use of tris(pentafluorophenyl)borane as the Lewis acid are required for obtaining the γ-alkylated syn-product selectively. In cases of α-chiral aldehydes, Felkin-Anh selectivity was observed.
UR - http://www.scopus.com/inward/record.url?scp=0035515483&partnerID=8YFLogxK
U2 - 10.1021/ol016677o
DO - 10.1021/ol016677o
M3 - Article
C2 - 11678708
AN - SCOPUS:0035515483
VL - 3
SP - 3561
EP - 3564
JO - Organic letters
JF - Organic letters
SN - 1523-7060
IS - 22
ER -