TY - JOUR

T1 - Plastidial retrograde signalling--a true "plastid factor" or just metabolite signatures?

AU - Pfannschmidt, Thomas

N1 - Funding information: This article was inspired by discussions with students via email and at a PhD workshop on “Chloroplasts” held in June 2009 in Gothenburg organised by Henrik Aronsson and Anastina Sandelius. It was also influenced by countless discussions with the members of my lab, the members of the DFG research group “Retrograde signalling in plants” ( http://www2.hu-berlin.de/dfg-forschergruppe804/ ) and many, many colleagues on several occasions, especially at the 1. Congress on Plant Retrograde Signalling held in October 2009 in Berlin organised by Bernhard Grimm. Thanks to all of them for sharing thoughts and criticisms, even if because of space limitations some points seem short. The work of my group is supported by grants from the Deutsche Forschungsgemeinschaft (PF 323/4 and PF 323/5).

PY - 2010/8

Y1 - 2010/8

N2 - The genetic compartments of plant cells, nuclei, plastids and mitochondria exchange information by anterograde (nucleus-to-organelle) and retrograde (organelle-to-nucleus) signalling. These avenues of communication coordinate activities during the organelles' development and function. Despite extensive research retrograde signalling remains poorly understood. The proposed cytosolic signalling pathways and the putative organellar signalling molecules remain elusive, and a clear functional distinction from the signalling cascades of other cellular perception systems (i.e. photoreceptors or phytohormones) is difficult to obtain. Notwithstanding the stagnant progress, some basic assumptions about the process have remained virtually unchanged for many years, potentially obstructing the view on alternative routes for retrograde communication. Here, I critically assess the current models of retrograde signalling and discuss novel ideas and potential connections.

AB - The genetic compartments of plant cells, nuclei, plastids and mitochondria exchange information by anterograde (nucleus-to-organelle) and retrograde (organelle-to-nucleus) signalling. These avenues of communication coordinate activities during the organelles' development and function. Despite extensive research retrograde signalling remains poorly understood. The proposed cytosolic signalling pathways and the putative organellar signalling molecules remain elusive, and a clear functional distinction from the signalling cascades of other cellular perception systems (i.e. photoreceptors or phytohormones) is difficult to obtain. Notwithstanding the stagnant progress, some basic assumptions about the process have remained virtually unchanged for many years, potentially obstructing the view on alternative routes for retrograde communication. Here, I critically assess the current models of retrograde signalling and discuss novel ideas and potential connections.

KW - Cell Nucleus/metabolism

KW - Mitochondria/metabolism

KW - Plant Cells

KW - Plants/metabolism

KW - Plastids/metabolism

KW - Signal Transduction

U2 - 10.1016/j.tplants.2010.05.009

DO - 10.1016/j.tplants.2010.05.009

M3 - Article

C2 - 20580596

VL - 15

SP - 427

EP - 435

JO - Trends in plant science

JF - Trends in plant science

SN - 1360-1385

IS - 8

ER -