Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms

Publikation: Beitrag in FachzeitschriftÜbersichtsarbeitForschungPeer-Review

Autoren

  • Rocco Giordano
  • Zeinab Saii
  • Malthe Fredsgaard
  • Laura Sini Sofia Hulkko
  • Thomas Bouet Guldbæk Poulsen
  • Mikkel Eggert Thomsen
  • Nanna Henneberg
  • Silvana Maria Zucolotto
  • Lars Arendt-Nielsen
  • Jutta Papenbrock
  • Mette Hedegaard Thomsen
  • Allan Stensballe

Organisationseinheiten

Externe Organisationen

  • Aalborg University
  • Universidade Federal de Santa Catarina
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Aufsatznummer3140
FachzeitschriftMOLECULES
Jahrgang26
Ausgabenummer11
PublikationsstatusVeröffentlicht - 24 Mai 2021

Abstract

The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.

ASJC Scopus Sachgebiete

Zitieren

Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms. / Giordano, Rocco; Saii, Zeinab; Fredsgaard, Malthe et al.
in: MOLECULES, Jahrgang 26, Nr. 11, 3140, 24.05.2021.

Publikation: Beitrag in FachzeitschriftÜbersichtsarbeitForschungPeer-Review

Giordano, R, Saii, Z, Fredsgaard, M, Hulkko, LSS, Poulsen, TBG, Thomsen, ME, Henneberg, N, Zucolotto, SM, Arendt-Nielsen, L, Papenbrock, J, Thomsen, MH & Stensballe, A 2021, 'Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms', MOLECULES, Jg. 26, Nr. 11, 3140. https://doi.org/10.3390/molecules26113140, https://doi.org/10.15488/14481
Giordano, R., Saii, Z., Fredsgaard, M., Hulkko, L. S. S., Poulsen, T. B. G., Thomsen, M. E., Henneberg, N., Zucolotto, S. M., Arendt-Nielsen, L., Papenbrock, J., Thomsen, M. H., & Stensballe, A. (2021). Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms. MOLECULES, 26(11), Artikel 3140. https://doi.org/10.3390/molecules26113140, https://doi.org/10.15488/14481
Giordano R, Saii Z, Fredsgaard M, Hulkko LSS, Poulsen TBG, Thomsen ME et al. Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms. MOLECULES. 2021 Mai 24;26(11):3140. doi: 10.3390/molecules26113140, 10.15488/14481
Giordano, Rocco ; Saii, Zeinab ; Fredsgaard, Malthe et al. / Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms. in: MOLECULES. 2021 ; Jahrgang 26, Nr. 11.
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abstract = "The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.",
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T1 - Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms

AU - Giordano, Rocco

AU - Saii, Zeinab

AU - Fredsgaard, Malthe

AU - Hulkko, Laura Sini Sofia

AU - Poulsen, Thomas Bouet Guldbæk

AU - Thomsen, Mikkel Eggert

AU - Henneberg, Nanna

AU - Zucolotto, Silvana Maria

AU - Arendt-Nielsen, Lars

AU - Papenbrock, Jutta

AU - Thomsen, Mette Hedegaard

AU - Stensballe, Allan

N1 - Funding Information: This review was funded from the European Union?s Horizon 2020 research and innovation programme under Grant Agreement No 862834.

PY - 2021/5/24

Y1 - 2021/5/24

N2 - The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.

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KW - Halophytes

KW - Hydroxycinnamic acid

KW - Inflammation

KW - Nutraceuticals

KW - Secondary metabolites

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U2 - 10.3390/molecules26113140

DO - 10.3390/molecules26113140

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VL - 26

JO - MOLECULES

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SN - 1420-3049

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