Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Autoren

  • A. Heisterkamp
  • T. Ripken
  • H. Lubatschowski
  • H. Welling
  • W. Drommer
  • E. Lu�tkefels
  • T. Mamom
  • W. Ertmer

Organisationseinheiten

Externe Organisationen

  • Laser Zentrum Hannover e.V. (LZH)
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Titel des SammelwerksOphthalmic Technologies XI;
Seiten246-254
Seitenumfang9
PublikationsstatusVeröffentlicht - 7 Juni 2001
VeranstaltungBios 2001 The International Symposium on Biomedical Optics - San Jose, CA, USA / Vereinigte Staaten
Dauer: 20 Jan. 200126 Jan. 2001

Publikationsreihe

NameProceedings of SPIE - The International Society for Optical Engineering
Band4245
ISSN (Print)0277-786X

Abstract

Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.

ASJC Scopus Sachgebiete

Zitieren

Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses. / Heisterkamp, A.; Ripken, T.; Lubatschowski, H. et al.
Ophthalmic Technologies XI;. 2001. S. 246-254 (Proceedings of SPIE - The International Society for Optical Engineering; Band 4245).

Publikation: Beitrag in Buch/Bericht/Sammelwerk/KonferenzbandAufsatz in KonferenzbandForschungPeer-Review

Heisterkamp, A, Ripken, T, Lubatschowski, H, Welling, H, Drommer, W, Lu�tkefels, E, Mamom, T & Ertmer, W 2001, Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses. in Ophthalmic Technologies XI;. Proceedings of SPIE - The International Society for Optical Engineering, Bd. 4245, S. 246-254, Bios 2001 The International Symposium on Biomedical Optics, San Jose, CA, USA / Vereinigte Staaten, 20 Jan. 2001. https://doi.org/10.1117/12.429279
Heisterkamp, A., Ripken, T., Lubatschowski, H., Welling, H., Drommer, W., Lu�tkefels, E., Mamom, T., & Ertmer, W. (2001). Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses. In Ophthalmic Technologies XI; (S. 246-254). (Proceedings of SPIE - The International Society for Optical Engineering; Band 4245). https://doi.org/10.1117/12.429279
Heisterkamp A, Ripken T, Lubatschowski H, Welling H, Drommer W, Lu�tkefels E et al. Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses. in Ophthalmic Technologies XI;. 2001. S. 246-254. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.429279
Heisterkamp, A. ; Ripken, T. ; Lubatschowski, H. et al. / Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses. Ophthalmic Technologies XI;. 2001. S. 246-254 (Proceedings of SPIE - The International Society for Optical Engineering).
Download
@inproceedings{1d4a57ceba2c4ecc8913e52dd50f2bb1,
title = "Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses",
abstract = "Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.",
keywords = "Femtosecond laser, Laser pulses, Photodisruption, Photodissociation, Refractive surgery, Ultrashort",
author = "A. Heisterkamp and T. Ripken and H. Lubatschowski and H. Welling and W. Drommer and E. Lu�tkefels and T. Mamom and W. Ertmer",
year = "2001",
month = jun,
day = "7",
doi = "10.1117/12.429279",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
pages = "246--254",
booktitle = "Ophthalmic Technologies XI;",
note = "Bios 2001 The International Symposium on Biomedical Optics ; Conference date: 20-01-2001 Through 26-01-2001",

}

Download

TY - GEN

T1 - Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses

AU - Heisterkamp, A.

AU - Ripken, T.

AU - Lubatschowski, H.

AU - Welling, H.

AU - Drommer, W.

AU - Lu�tkefels, E.

AU - Mamom, T.

AU - Ertmer, W.

PY - 2001/6/7

Y1 - 2001/6/7

N2 - Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.

AB - Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.

KW - Femtosecond laser

KW - Laser pulses

KW - Photodisruption

KW - Photodissociation

KW - Refractive surgery

KW - Ultrashort

UR - http://www.scopus.com/inward/record.url?scp=0034859277&partnerID=8YFLogxK

U2 - 10.1117/12.429279

DO - 10.1117/12.429279

M3 - Conference contribution

AN - SCOPUS:0034859277

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 246

EP - 254

BT - Ophthalmic Technologies XI;

T2 - Bios 2001 The International Symposium on Biomedical Optics

Y2 - 20 January 2001 through 26 January 2001

ER -