Details
| Titel in Übersetzung | Optimisation of the laser parameters for intrastromal incisions using ultrashort laser pulses |
|---|---|
| Originalsprache | Deutsch |
| Seiten (von - bis) | 623-628 |
| Seitenumfang | 6 |
| Fachzeitschrift | OPHTHALMOLOGE |
| Jahrgang | 98 |
| Ausgabenummer | 7 |
| Publikationsstatus | Veröffentlicht - 16 Aug. 2001 |
Abstract
Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.
Schlagwörter
- Intrastromal, Photodisruption, Refractive surgery, Ultrashort laser pulses
ASJC Scopus Sachgebiete
- Medizin (insg.)
- Ophthalmologie
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in: OPHTHALMOLOGE, Jahrgang 98, Nr. 7, 16.08.2001, S. 623-628.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Optimierung der laserparameter für die intrastromale schnittführung mittels ultrakurzer laserpulse
AU - Heisterkamp, A.
AU - Ripken, T.
AU - Lütkefles, E.
AU - Drommer, W.
AU - Lubatschowski, H.
AU - Welling, H.
AU - Ertmer, W.
PY - 2001/8/16
Y1 - 2001/8/16
N2 - Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.
AB - Background: With the assistance of ultrashort laser pulses (ca. 200 fs pulse duration) it is possible to perform precise incisions inside the corneal stroma with a width of a few microns. The advantage of ultrashort pulses is that the required energy of a few microjoules is more than an order of magnitude lower compared with longer pulse durations, i.e. ps or ns pulses. Therefore, the secondary effects, such as thermal and mechanical damage to the surrounding tissue and the amount of radiation reaching the retina, are reduced. This method of intrastromal photodisruption allows a very well defined deposition of energy within the laser focus inside the corneal stroma, accompanied by minimal collateral damage. Methods: The possibilities of performing intrastromal cuts using fs-laser pulses at a wavelength of 780 nm and pulse durations of 200 fs were studied using a titanium-sapphire laser system. The treated tissue samples were analysed by light and scanning electron microscopy to determine incision quality, reproducibility and achievable accuracy. The mechanical side effects of fs-photodisruption inside the surrounding tissue were analysed by pressure measurements using pyroelectric transducers. Conclusion: The thermal and mechanical side-effects of this method are very low and comparable to the effects during excimer treatment. Therefore an application of ultrashort laser pulses in refractive surgery appears to be a feasible alternative.
KW - Intrastromal
KW - Photodisruption
KW - Refractive surgery
KW - Ultrashort laser pulses
UR - http://www.scopus.com/inward/record.url?scp=0034903911&partnerID=8YFLogxK
U2 - 10.1007/s003470170097
DO - 10.1007/s003470170097
M3 - Artikel
C2 - 11490739
AN - SCOPUS:0034903911
VL - 98
SP - 623
EP - 628
JO - OPHTHALMOLOGE
JF - OPHTHALMOLOGE
SN - 0941-293X
IS - 7
ER -