Details
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 105007 |
| Fachzeitschrift | Journal of biomedical optics |
| Jahrgang | 22 |
| Ausgabenummer | 10 |
| Publikationsstatus | Veröffentlicht - 1 Okt. 2017 |
Abstract
Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths (>400nm) for investigating the perilymph behind the round window membrane in future.
ASJC Scopus Sachgebiete
- Werkstoffwissenschaften (insg.)
- Elektronische, optische und magnetische Materialien
- Werkstoffwissenschaften (insg.)
- Biomaterialien
- Physik und Astronomie (insg.)
- Atom- und Molekularphysik sowie Optik
- Ingenieurwesen (insg.)
- Biomedizintechnik
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in: Journal of biomedical optics, Jahrgang 22, Nr. 10, 105007, 01.10.2017.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Optical properties of the human round window membrane
AU - Höhl, Martin
AU - Detemple, Daphne
AU - Lyutenski, Stefan
AU - Leuteritz, Georg
AU - Varkentin, Arthur
AU - Schmitt, Heike Andrea
AU - Lenarz, Thomas
AU - Roth, Bernhard
AU - Meinhardt-Wollweber, Merve
AU - Morgner, Uwe
N1 - Funding information: We thank Peter Erfurt and Dr. Nils Prenzler for providing additional samples. This work was supported by the DFG Cluster of Excellence EXC 1077/1 “Hearing4all.”
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths (>400nm) for investigating the perilymph behind the round window membrane in future.
AB - Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths (>400nm) for investigating the perilymph behind the round window membrane in future.
KW - fiber optic probe
KW - perilymph
KW - round window membrane
KW - scattering
KW - transmission
UR - http://www.scopus.com/inward/record.url?scp=85032993208&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.22.10.105007
DO - 10.1117/1.JBO.22.10.105007
M3 - Article
C2 - 29076311
AN - SCOPUS:85032993208
VL - 22
JO - Journal of biomedical optics
JF - Journal of biomedical optics
SN - 1083-3668
IS - 10
M1 - 105007
ER -