Details
| Originalsprache | Englisch |
|---|---|
| Fachzeitschrift | Natural product reports |
| Jahrgang | 11 |
| Publikationsstatus | Veröffentlicht - 23 Sept. 2022 |
Abstract
Covering: up to 2022 The report provides a broad approach to deciphering the evolution of coenzyme biosynthetic pathways. Here, these various pathways are analyzed with respect to the coenzymes required for this purpose. Coenzymes whose biosynthesis relies on a large number of coenzyme-mediated reactions probably appeared on the scene at a later stage of biological evolution, whereas the biosyntheses of pyridoxal phosphate (PLP) and nicotinamide (NAD+) require little additional coenzymatic support and are therefore most likely very ancient biosynthetic pathways.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Pharmakologie, Toxikologie und Pharmazie (insg.)
- Wirkstoffforschung
- Chemie (insg.)
- Organische Chemie
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in: Natural product reports, Jahrgang 11, 23.09.2022.
Publikation: Beitrag in Fachzeitschrift › Übersichtsarbeit › Forschung › Peer-Review
}
TY - JOUR
T1 - On the evolution of coenzyme biosynthesis
AU - Kirschning, Andreas
PY - 2022/9/23
Y1 - 2022/9/23
N2 - Covering: up to 2022 The report provides a broad approach to deciphering the evolution of coenzyme biosynthetic pathways. Here, these various pathways are analyzed with respect to the coenzymes required for this purpose. Coenzymes whose biosynthesis relies on a large number of coenzyme-mediated reactions probably appeared on the scene at a later stage of biological evolution, whereas the biosyntheses of pyridoxal phosphate (PLP) and nicotinamide (NAD+) require little additional coenzymatic support and are therefore most likely very ancient biosynthetic pathways.
AB - Covering: up to 2022 The report provides a broad approach to deciphering the evolution of coenzyme biosynthetic pathways. Here, these various pathways are analyzed with respect to the coenzymes required for this purpose. Coenzymes whose biosynthesis relies on a large number of coenzyme-mediated reactions probably appeared on the scene at a later stage of biological evolution, whereas the biosyntheses of pyridoxal phosphate (PLP) and nicotinamide (NAD+) require little additional coenzymatic support and are therefore most likely very ancient biosynthetic pathways.
UR - http://www.scopus.com/inward/record.url?scp=85139950738&partnerID=8YFLogxK
U2 - 10.1039/d2np00037g
DO - 10.1039/d2np00037g
M3 - Review article
AN - SCOPUS:85139950738
VL - 11
JO - Natural product reports
JF - Natural product reports
SN - 0265-0568
ER -