Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 320-325 |
| Seitenumfang | 6 |
| Fachzeitschrift | Laboratory animals |
| Jahrgang | 42 |
| Ausgabenummer | 3 |
| Publikationsstatus | Veröffentlicht - 1 Juli 2008 |
Abstract
In an experimental study, we evaluated acoustic immittance in rabbits in order to use these data as normative values for further experimental investigations. This study is the first experimental evaluation of both conventional 226 Hz and multifrequency tympanometry (MFT) in rabbits. For the investigation, we used 33 female New Zealand rabbits weighing 3.2 - 4.4 kg and aged six months. Bilateral measurements using conventional 226 Hz and MFT were performed under general anaesthetic. A 226 Hz tympanogram was recorded for all animals by conducting an air pressure sweep from +200 to -400 daPa at a rate of 50 daPa/s. Subsequent tympanograms were recorded over a wide frequency range from 250 to 2000 Hz. The acoustic impedance device used in this study provided reproducible and evaluable tympanograms. The applied tone frequency of 226 Hz proved to be especially suitable for determining compliance. Normative data obtained from our study reveal the resonance frequency to be 1368±205 standard deviation (SD) for the right side and 1413±216 SD for the left side. The values for physiological acoustic immittance of the middle ear in the rabbit obtained here can serve as normative data in subsequent experimental animal studies.
ASJC Scopus Sachgebiete
- Agrar- und Biowissenschaften (insg.)
- Nutztierwissenschaften und Zoologie
- Veterinärmedizin (insg.)
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in: Laboratory animals, Jahrgang 42, Nr. 3, 01.07.2008, S. 320-325.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Normative data of multifrequency tympanometry in rabbits
AU - Stieve, Martin
AU - Hedrich, Hans
AU - Mojallal, Hamidreza
AU - Behrens, Peter
AU - Müller, Peter
AU - Lenarz, Thomas
N1 - Funding information: This project is supported by the German Research Foundation (DFG) within the collaborative research programme SFB 599/D1.
PY - 2008/7/1
Y1 - 2008/7/1
N2 - In an experimental study, we evaluated acoustic immittance in rabbits in order to use these data as normative values for further experimental investigations. This study is the first experimental evaluation of both conventional 226 Hz and multifrequency tympanometry (MFT) in rabbits. For the investigation, we used 33 female New Zealand rabbits weighing 3.2 - 4.4 kg and aged six months. Bilateral measurements using conventional 226 Hz and MFT were performed under general anaesthetic. A 226 Hz tympanogram was recorded for all animals by conducting an air pressure sweep from +200 to -400 daPa at a rate of 50 daPa/s. Subsequent tympanograms were recorded over a wide frequency range from 250 to 2000 Hz. The acoustic impedance device used in this study provided reproducible and evaluable tympanograms. The applied tone frequency of 226 Hz proved to be especially suitable for determining compliance. Normative data obtained from our study reveal the resonance frequency to be 1368±205 standard deviation (SD) for the right side and 1413±216 SD for the left side. The values for physiological acoustic immittance of the middle ear in the rabbit obtained here can serve as normative data in subsequent experimental animal studies.
AB - In an experimental study, we evaluated acoustic immittance in rabbits in order to use these data as normative values for further experimental investigations. This study is the first experimental evaluation of both conventional 226 Hz and multifrequency tympanometry (MFT) in rabbits. For the investigation, we used 33 female New Zealand rabbits weighing 3.2 - 4.4 kg and aged six months. Bilateral measurements using conventional 226 Hz and MFT were performed under general anaesthetic. A 226 Hz tympanogram was recorded for all animals by conducting an air pressure sweep from +200 to -400 daPa at a rate of 50 daPa/s. Subsequent tympanograms were recorded over a wide frequency range from 250 to 2000 Hz. The acoustic impedance device used in this study provided reproducible and evaluable tympanograms. The applied tone frequency of 226 Hz proved to be especially suitable for determining compliance. Normative data obtained from our study reveal the resonance frequency to be 1368±205 standard deviation (SD) for the right side and 1413±216 SD for the left side. The values for physiological acoustic immittance of the middle ear in the rabbit obtained here can serve as normative data in subsequent experimental animal studies.
KW - Acoustic immittance
KW - Animal model
KW - Multifrequency tympanometry
KW - Organisms and models
KW - White rabbit
UR - http://www.scopus.com/inward/record.url?scp=47749123450&partnerID=8YFLogxK
U2 - 10.1258/la.2007.007080
DO - 10.1258/la.2007.007080
M3 - Article
C2 - 18625586
AN - SCOPUS:47749123450
VL - 42
SP - 320
EP - 325
JO - Laboratory animals
JF - Laboratory animals
SN - 0023-6772
IS - 3
ER -