Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Sian M. Cooper
  • Russell J. Cox
  • John Crosby
  • Matthew P. Crump
  • Joanne Hothersall
  • Wanpen Laosripaiboon
  • Thomas J. Simpson
  • Christopher M. Thomas

Externe Organisationen

  • University of Birmingham
  • University of Bristol
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)1179-1181
Seitenumfang3
FachzeitschriftChemical communications
Ausgabenummer9
PublikationsstatusVeröffentlicht - 7 März 2005
Extern publiziertJa

Abstract

Mutation of the mupW gene in the mupirocin biosynthetic gene cluster in Pseudomonas fluorescens results in efficient production of a novel pseudomonic acid metabolite, mupirocin W, which lacks the characteristic tetrahydropyran ring, and reveals the role of the mupW gene in pseudomonic acid biosynthesis.

ASJC Scopus Sachgebiete

Zitieren

Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster. / Cooper, Sian M.; Cox, Russell J.; Crosby, John et al.
in: Chemical communications, Nr. 9, 07.03.2005, S. 1179-1181.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Cooper, SM, Cox, RJ, Crosby, J, Crump, MP, Hothersall, J, Laosripaiboon, W, Simpson, TJ & Thomas, CM 2005, 'Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster', Chemical communications, Nr. 9, S. 1179-1181. https://doi.org/10.1039/b414781b
Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Laosripaiboon, W., Simpson, T. J., & Thomas, C. M. (2005). Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster. Chemical communications, (9), 1179-1181. https://doi.org/10.1039/b414781b
Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J, Laosripaiboon W et al. Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster. Chemical communications. 2005 Mär 7;(9):1179-1181. doi: 10.1039/b414781b
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AU - Crosby, John

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AU - Hothersall, Joanne

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