Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Autoren

  • Ji'En Wu
  • Sian M. Cooper
  • Russell J. Cox
  • John Crosby
  • Matthew P. Crump
  • Joanne Hothersall
  • Thomas J. Simpson
  • Christopher M. Thomas
  • Christine L. Willis

Externe Organisationen

  • University of Bristol
  • University of Birmingham
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)2040-2042
Seitenumfang3
FachzeitschriftChemical communications
Ausgabenummer20
PublikationsstatusVeröffentlicht - 1 Jan. 2007
Extern publiziertJa

Abstract

Mutation of the HMG-CoA synthase encoding mupH gene in Pseudomonas fluorescens gives rise to a new metabolite formed from a truncated polyketide intermediate, providing in vivo evidence for the roles of mupH and cognate genes found in several "AT-less" and other bacterial PKS gene clusters responsible for the biosynthesis of diverse metabolites containing acetate/propionate derived side chains.

ASJC Scopus Sachgebiete

Zitieren

Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens. / Wu, Ji'En; Cooper, Sian M.; Cox, Russell J. et al.
in: Chemical communications, Nr. 20, 01.01.2007, S. 2040-2042.

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Wu, JE, Cooper, SM, Cox, RJ, Crosby, J, Crump, MP, Hothersall, J, Simpson, TJ, Thomas, CM & Willis, CL 2007, 'Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens', Chemical communications, Nr. 20, S. 2040-2042. https://doi.org/10.1039/b700613f
Wu, JE., Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Simpson, T. J., Thomas, C. M., & Willis, C. L. (2007). Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens. Chemical communications, (20), 2040-2042. https://doi.org/10.1039/b700613f
Wu JE, Cooper SM, Cox RJ, Crosby J, Crump MP, Hothersall J et al. Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens. Chemical communications. 2007 Jan 1;(20):2040-2042. doi: 10.1039/b700613f
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AU - Crosby, John

AU - Crump, Matthew P.

AU - Hothersall, Joanne

AU - Simpson, Thomas J.

AU - Thomas, Christopher M.

AU - Willis, Christine L.

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