Details
| Originalsprache | Englisch |
|---|---|
| Titel des Sammelwerks | Biomedical Fiber Optic Instrumentation |
| Seiten | 555-562 |
| Seitenumfang | 8 |
| Publikationsstatus | Veröffentlicht - 28 Juli 1994 |
| Extern publiziert | Ja |
| Veranstaltung | OE/LASE '94 - Los Angeles, CA, USA / Vereinigte Staaten Dauer: 23 Jan. 1994 → 29 Jan. 1994 |
Publikationsreihe
| Name | Proceedings of SPIE - The International Society for Optical Engineering |
|---|---|
| Herausgeber (Verlag) | SPIE |
| Band | 2131 |
| ISSN (Print) | 0277-786X |
Abstract
In clinical chemistry, sensors are needed that can detect small analyte concentrations in complex physiological media. During hemodialysis it is especially important to determine the urea concentration on line in order to monitor the completion of the purification. Since no substrate flow is required in the sensor head, this technology is especially suited for monitoring in physiological solutions (no electrical contact to the patient is necessary). Biosensors were developed on the basis of optical pH sensors. This was accomplished by iminobilising enzymes directly on the sensor head. The pH shift, caused by the enzymatic reaction, is detected by the pH sensor. A multichannel fluorimeter was developed in order to monitor various analytes simultaneously, and possible pH changes in the medium. A urea biosensor was characterised and applied for urea detection during a simulated dialysis.
ASJC Scopus Sachgebiete
- Werkstoffwissenschaften (insg.)
- Elektronische, optische und magnetische Materialien
- Physik und Astronomie (insg.)
- Physik der kondensierten Materie
- Informatik (insg.)
- Angewandte Informatik
- Mathematik (insg.)
- Angewandte Mathematik
- Ingenieurwesen (insg.)
- Elektrotechnik und Elektronik
Zitieren
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- BibTex
- RIS
Biomedical Fiber Optic Instrumentation. 1994. S. 555-562 (Proceedings of SPIE - The International Society for Optical Engineering; Band 2131).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Aufsatz in Konferenzband › Forschung › Peer-Review
}
TY - GEN
T1 - Multicomponent fiberoptical biosensor for use in hemodialysis monitoring
AU - Muller, Cord
AU - Schubert, Florian
AU - Scheper, Thomas
PY - 1994/7/28
Y1 - 1994/7/28
N2 - In clinical chemistry, sensors are needed that can detect small analyte concentrations in complex physiological media. During hemodialysis it is especially important to determine the urea concentration on line in order to monitor the completion of the purification. Since no substrate flow is required in the sensor head, this technology is especially suited for monitoring in physiological solutions (no electrical contact to the patient is necessary). Biosensors were developed on the basis of optical pH sensors. This was accomplished by iminobilising enzymes directly on the sensor head. The pH shift, caused by the enzymatic reaction, is detected by the pH sensor. A multichannel fluorimeter was developed in order to monitor various analytes simultaneously, and possible pH changes in the medium. A urea biosensor was characterised and applied for urea detection during a simulated dialysis.
AB - In clinical chemistry, sensors are needed that can detect small analyte concentrations in complex physiological media. During hemodialysis it is especially important to determine the urea concentration on line in order to monitor the completion of the purification. Since no substrate flow is required in the sensor head, this technology is especially suited for monitoring in physiological solutions (no electrical contact to the patient is necessary). Biosensors were developed on the basis of optical pH sensors. This was accomplished by iminobilising enzymes directly on the sensor head. The pH shift, caused by the enzymatic reaction, is detected by the pH sensor. A multichannel fluorimeter was developed in order to monitor various analytes simultaneously, and possible pH changes in the medium. A urea biosensor was characterised and applied for urea detection during a simulated dialysis.
UR - http://www.scopus.com/inward/record.url?scp=85033106478&partnerID=8YFLogxK
U2 - 10.1117/12.180755
DO - 10.1117/12.180755
M3 - Conference contribution
AN - SCOPUS:85033106478
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 555
EP - 562
BT - Biomedical Fiber Optic Instrumentation
T2 - OE/LASE '94
Y2 - 23 January 1994 through 29 January 1994
ER -