TY - JOUR

T1 - Microfluidics in Biotechnology

T2 - Quo Vadis

AU - Winkler, Steffen

AU - Grünberger, Alexander

AU - Bahnemann, Janina

N1 - Funding Information: The authors would like to thank Niklas M. Epping (Institute of Technical Chemistry, Leibniz University Hannover, Germany) and Dr. Natalie Rotermund (Institute of Zoology, University of Hamburg, Germany) for their contribution in creating the illustrations.

PY - 2022

Y1 - 2022

N2 - The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements.

AB - The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements.

KW - Biochemical engineering

KW - Industrial biotechnology

KW - Lab-on-a-chip

KW - Medical biotechnology

KW - Microfluidic screening

KW - Microfluidics

KW - Nanofluidics

KW - Organ-on-a-chip

KW - Point-of-care

KW - Point-of-use

UR - http://www.scopus.com/inward/record.url?scp=85135370351&partnerID=8YFLogxK

U2 - 10.1007/10_2020_162

DO - 10.1007/10_2020_162

M3 - Article

C2 - 33495924

VL - 179

SP - 355

EP - 380

JO - Advances in Biochemical Engineering/Biotechnology

JF - Advances in Biochemical Engineering/Biotechnology

SN - 0724-6145

ER -