TY - CHAP

T1 - Medicinal Uses, Phytochemistry, and Pharmacological Properties of Acorus calamus

AU - Qamar, Muhammad

AU - Ahmad, Naveed

AU - Ismail, Tariq

AU - Esatbeyoglu, Tuba

AU - Akhtar, Saeed

AU - Mubarak, Muhammad S.

PY - 2023/6/15

Y1 - 2023/6/15

N2 - Acorus calamus, a potent bio-reserve with medicinal value, has been used to treat human diseases since prehistoric times in China and India. It has the potential of assisting and overhauling the healthcare system in the future. Regarding medicinal use, the plant has been used to treat neurological, respiratory, metabolic, hepatic, and nephrotic illnesses. Rhizomes and leaves are believed to possess stimulant, carminative, antispasmodic, anthelmintic, sedative, aromatic, and other properties and are used to address disorders such as mental illness, diabetes, eczema, convulsions, diarrhoea, abdominal and glandular tumours, hair loss, fevers, epilepsy, neuralgia, dysentery, arthritis, bronchitis, and others. Phytochemical characterization reveals the identification and isolation of approximately 145 constituents (secondary metabolites) including alkaloids, monoterpenes, phenylpropanoids, saponins, sesquiterpenes, and others from leaves and rhizomes. Evidence exists that the bioactivity and pharmacotherapeutics of this plant are mainly accredited to eugenol, asarones (a and Β), and sesquiterpenoids. Its numerous extracts (from different plant parts) exhibit potent pharmacological activities. The most obvious in vivo and in vitro (clinical and pre-clinical) evidence shows that the plant exhibits antihypertensive, antidiabetic, anti-obesity, antioxidant, immunomodulatory, anti-inflammatory, neuroprotective, and anti-convulsant activity. Despite these activities, toxicity studies, safety concerns, and quality control are required. It is hoped that this chapter will provide a firm base for further research.

AB - Acorus calamus, a potent bio-reserve with medicinal value, has been used to treat human diseases since prehistoric times in China and India. It has the potential of assisting and overhauling the healthcare system in the future. Regarding medicinal use, the plant has been used to treat neurological, respiratory, metabolic, hepatic, and nephrotic illnesses. Rhizomes and leaves are believed to possess stimulant, carminative, antispasmodic, anthelmintic, sedative, aromatic, and other properties and are used to address disorders such as mental illness, diabetes, eczema, convulsions, diarrhoea, abdominal and glandular tumours, hair loss, fevers, epilepsy, neuralgia, dysentery, arthritis, bronchitis, and others. Phytochemical characterization reveals the identification and isolation of approximately 145 constituents (secondary metabolites) including alkaloids, monoterpenes, phenylpropanoids, saponins, sesquiterpenes, and others from leaves and rhizomes. Evidence exists that the bioactivity and pharmacotherapeutics of this plant are mainly accredited to eugenol, asarones (a and Β), and sesquiterpenoids. Its numerous extracts (from different plant parts) exhibit potent pharmacological activities. The most obvious in vivo and in vitro (clinical and pre-clinical) evidence shows that the plant exhibits antihypertensive, antidiabetic, anti-obesity, antioxidant, immunomodulatory, anti-inflammatory, neuroprotective, and anti-convulsant activity. Despite these activities, toxicity studies, safety concerns, and quality control are required. It is hoped that this chapter will provide a firm base for further research.

UR - http://www.scopus.com/inward/record.url?scp=85169401598&partnerID=8YFLogxK

U2 - 10.1201/9781003256830-6

DO - 10.1201/9781003256830-6

M3 - Contribution to book/anthology

AN - SCOPUS:85169401598

SN - 9781032185408

SP - 89

EP - 105

BT - Aquatic Medicinal Plants

ER -