Details
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 4229 |
| Fachzeitschrift | Nanomaterials |
| Jahrgang | 12 |
| Ausgabenummer | 23 |
| Publikationsstatus | Veröffentlicht - 28 Nov. 2022 |
Abstract
Laser processing of dental implant surfaces is becoming a more widespread replacement for classical techniques due to its undeniable advantages, including control of oxide formation and structure and surface relief at the microscale. Thus, using a laser, we created several biomimetic topographies of various shapes on the surface of titanium screw-shaped implants to research their success and survival rates. A distinctive feature of the topographies is the presence of “µ-rooms”, which are special spaces created by the depressions and elevations and are analogous to the µ-sized room in which the osteocyte will potentially live. We conducted the comparable in vivo study using dental implants with continuous (G-topography with µ-canals), discrete (S-topography with μ-cavities), and irregular (I-topography) laser-induced topographies. A histological analysis performed with the statistical method (with p-value less than 0.05) was conducted, which showed that G-topography had the highest BIC parameter and contained the highest number of mature osteocytes, indicating the best secondary stability and osseointegration.
ASJC Scopus Sachgebiete
- Chemische Verfahrenstechnik (insg.)
- Allgemeine chemische Verfahrenstechnik
- Werkstoffwissenschaften (insg.)
- Allgemeine Materialwissenschaften
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in: Nanomaterials, Jahrgang 12, Nr. 23, 4229, 28.11.2022.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Laser-Induced µ-Rooms for Osteocytes on Implant Surface
T2 - An In Vivo Study
AU - Veiko, Vadim
AU - Karlagina, Yuliya
AU - Zernitckaia, Ekaterina
AU - Egorova, Elena
AU - Radaev, Maxim
AU - Yaremenko, Andrey
AU - Chernenko, Gennadiy
AU - Romanov, Valery
AU - Shchedrina, Nadezhda
AU - Ivanova, Elena
AU - Chichkov, Boris
AU - Odintsova, Galina
N1 - Funding Information: This work was supported by the Ministry of Science and Higher Education of the Russian Federation research agreement No. 075-11-2021-045 of 24 June 2021, project title “Development of high-tech production of equipment and technologies for laser functionalization of the surface of medical products” (within the framework of decree of the Government of the Russian Federation No. 218 of 9 April 2010).
PY - 2022/11/28
Y1 - 2022/11/28
N2 - Laser processing of dental implant surfaces is becoming a more widespread replacement for classical techniques due to its undeniable advantages, including control of oxide formation and structure and surface relief at the microscale. Thus, using a laser, we created several biomimetic topographies of various shapes on the surface of titanium screw-shaped implants to research their success and survival rates. A distinctive feature of the topographies is the presence of “µ-rooms”, which are special spaces created by the depressions and elevations and are analogous to the µ-sized room in which the osteocyte will potentially live. We conducted the comparable in vivo study using dental implants with continuous (G-topography with µ-canals), discrete (S-topography with μ-cavities), and irregular (I-topography) laser-induced topographies. A histological analysis performed with the statistical method (with p-value less than 0.05) was conducted, which showed that G-topography had the highest BIC parameter and contained the highest number of mature osteocytes, indicating the best secondary stability and osseointegration.
AB - Laser processing of dental implant surfaces is becoming a more widespread replacement for classical techniques due to its undeniable advantages, including control of oxide formation and structure and surface relief at the microscale. Thus, using a laser, we created several biomimetic topographies of various shapes on the surface of titanium screw-shaped implants to research their success and survival rates. A distinctive feature of the topographies is the presence of “µ-rooms”, which are special spaces created by the depressions and elevations and are analogous to the µ-sized room in which the osteocyte will potentially live. We conducted the comparable in vivo study using dental implants with continuous (G-topography with µ-canals), discrete (S-topography with μ-cavities), and irregular (I-topography) laser-induced topographies. A histological analysis performed with the statistical method (with p-value less than 0.05) was conducted, which showed that G-topography had the highest BIC parameter and contained the highest number of mature osteocytes, indicating the best secondary stability and osseointegration.
KW - biocompatibility
KW - in vivo
KW - laser texturing
KW - osseointegration
KW - rabbit tibia
KW - titanium implants
KW - topography
UR - http://www.scopus.com/inward/record.url?scp=85143595779&partnerID=8YFLogxK
U2 - 10.3390/nano12234229
DO - 10.3390/nano12234229
M3 - Article
AN - SCOPUS:85143595779
VL - 12
JO - Nanomaterials
JF - Nanomaterials
SN - 2079-4991
IS - 23
M1 - 4229
ER -