Details
Originalsprache | Englisch |
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Titel des Sammelwerks | Ophthalmic Technologies XII |
Herausgeber (Verlag) | SPIE |
Seiten | 136-142 |
Seitenumfang | 7 |
Publikationsstatus | Veröffentlicht - 13 Juni 2002 |
Publikationsreihe
Name | Proceedings of SPIE-The International Society for Optical Engineering |
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Band | 4611 |
ISSN (Print) | 0277-786X |
Abstract
In order to perform refractive surgery, fs-laser pulses of 130 fs pulse duration were focussed into animal cornea. By focussing the radiation down to spot-sizes of 5 μm, very precise cuts could be achieved inside the treated eyes, accompanied with minimum collateral damage to the tissue by thermal or mechanical effects. Due to these low side effects, μm-cutting precisions at preparing of corneal flaps and lenticules can be achieved. Thus, animals studies with 8 living rabbits were performed, in which intrastromal lenticules and flaps were created and extracted. Woundhealing reactions were studied by histo-pathological analysis of the treated eyes in intervalls at one, 7, 14 and 28 days after surgery. The treated eyes showed mild woundhealing reactions with comparable results to what is known from Excimer-LASIK. Moreover the use of the fs-laser offered new possibilities in preparation of corneal flaps, providing advantages to the use of the mechanical keratome.
ASJC Scopus Sachgebiete
- Werkstoffwissenschaften (insg.)
- Elektronische, optische und magnetische Materialien
- Physik und Astronomie (insg.)
- Physik der kondensierten Materie
- Informatik (insg.)
- Angewandte Informatik
- Mathematik (insg.)
- Angewandte Mathematik
- Ingenieurwesen (insg.)
- Elektrotechnik und Elektronik
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Ophthalmic Technologies XII. SPIE, 2002. S. 136-142 (Proceedings of SPIE-The International Society for Optical Engineering; Band 4611).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Aufsatz in Konferenzband › Forschung › Peer-Review
}
TY - GEN
T1 - Intrastromal refractive surgery with ultrashort laser pulses in living animals
AU - Heisterkamp, Alexander
AU - Mamom, Thanongsak
AU - Kermani, Omid
AU - Drommer, Wolfgang
AU - Welling, Herbert
AU - Ertmer, Wolfgang
AU - Lubatschowski, Holger
PY - 2002/6/13
Y1 - 2002/6/13
N2 - In order to perform refractive surgery, fs-laser pulses of 130 fs pulse duration were focussed into animal cornea. By focussing the radiation down to spot-sizes of 5 μm, very precise cuts could be achieved inside the treated eyes, accompanied with minimum collateral damage to the tissue by thermal or mechanical effects. Due to these low side effects, μm-cutting precisions at preparing of corneal flaps and lenticules can be achieved. Thus, animals studies with 8 living rabbits were performed, in which intrastromal lenticules and flaps were created and extracted. Woundhealing reactions were studied by histo-pathological analysis of the treated eyes in intervalls at one, 7, 14 and 28 days after surgery. The treated eyes showed mild woundhealing reactions with comparable results to what is known from Excimer-LASIK. Moreover the use of the fs-laser offered new possibilities in preparation of corneal flaps, providing advantages to the use of the mechanical keratome.
AB - In order to perform refractive surgery, fs-laser pulses of 130 fs pulse duration were focussed into animal cornea. By focussing the radiation down to spot-sizes of 5 μm, very precise cuts could be achieved inside the treated eyes, accompanied with minimum collateral damage to the tissue by thermal or mechanical effects. Due to these low side effects, μm-cutting precisions at preparing of corneal flaps and lenticules can be achieved. Thus, animals studies with 8 living rabbits were performed, in which intrastromal lenticules and flaps were created and extracted. Woundhealing reactions were studied by histo-pathological analysis of the treated eyes in intervalls at one, 7, 14 and 28 days after surgery. The treated eyes showed mild woundhealing reactions with comparable results to what is known from Excimer-LASIK. Moreover the use of the fs-laser offered new possibilities in preparation of corneal flaps, providing advantages to the use of the mechanical keratome.
KW - fs-photodisruption
KW - Laser pulses
KW - Refractive surgery
KW - Ultrashort
UR - http://www.scopus.com/inward/record.url?scp=0036402253&partnerID=8YFLogxK
U2 - 10.1117/12.470587
DO - 10.1117/12.470587
M3 - Conference contribution
AN - SCOPUS:0036402253
T3 - Proceedings of SPIE-The International Society for Optical Engineering
SP - 136
EP - 142
BT - Ophthalmic Technologies XII
PB - SPIE
ER -