Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 7254-7266 |
| Seitenumfang | 13 |
| Fachzeitschrift | Journal of Bacteriology |
| Jahrgang | 187 |
| Ausgabenummer | 21 |
| Publikationsstatus | Veröffentlicht - Nov. 2005 |
| Extern publiziert | Ja |
Abstract
The gram-negative plant-pathogenic bacterium Xanthomonas campestris pv. vesicatoria is the causative agent of bacterial spot disease in pepper and tomato plants, which leads to economically important yield losses. This pathosystem has become a well-established model for studying bacterial infection strategies. Here, we present the whole-genome sequence of the pepper-pathogenic Xanthomonas campestris pv. vesicatoria strain 85-10, which comprises a 5.17-Mb circular chromosome and four plasmids. The genome has a high G+C content (64.75%) and signatures of extensive genome plasticity. Whole-genome comparisons revealed a gene order similar to both Xanthomonas axonopodis pv. citri and Xanthomonas campestris pv. campestris and a structure completely different from Xanthomonas oryzae pv. oryzae. A total of 548 coding sequences (12.2%) are unique to X. campestris pv. vesicatoria. In addition to a type III secretion system, which is essential for pathogenicity, the genome of strain 85-10 encodes all other types of protein secretion systems described so far in gram-negative bacteria. Remarkably, one of the putative type IV secretion systems encoded on the largest plasmid is similar to the Icm/Dot systems of the human pathogens Legionella pneumophila and Coxiella burnetii. Comparisons with other completely sequenced plant pathogens predicted six novel type III effector proteins and several other virulence factors, including adhesins, cell wall-degrading enzymes, and extracellular polysaccharides.
ASJC Scopus Sachgebiete
- Immunologie und Mikrobiologie (insg.)
- Mikrobiologie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Molekularbiologie
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in: Journal of Bacteriology, Jahrgang 187, Nr. 21, 11.2005, S. 7254-7266.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence
AU - Thieme, Frank
AU - Koebnik, Ralf
AU - Bekel, Thomas
AU - Berger, Carolin
AU - Boch, Jens
AU - Büttner, Daniela
AU - Caldana, Camila
AU - Gaigalat, Lars
AU - Goesmann, Alexander
AU - Kay, Sabine
AU - Kirchner, Oliver
AU - Lanz, Christa
AU - Linke, Burkhard
AU - McHardy, Alice C.
AU - Meyer, Folker
AU - Mittenhuber, Gerhard
AU - Nies, Dietrich H.
AU - Niesbach-Klösgen, Ulla
AU - Patschkowski, Thomas
AU - Rückert, Christian
AU - Rupp, Oliver
AU - Schneiker, Susanne
AU - Schuster, Stephan C.
AU - Vorhölter, Frank Jörg
AU - Weber, Ernst
AU - Pühler, Alfred
AU - Bonas, Ulla
AU - Bartels, Daniela
AU - Kaiser, Olaf
N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/11
Y1 - 2005/11
N2 - The gram-negative plant-pathogenic bacterium Xanthomonas campestris pv. vesicatoria is the causative agent of bacterial spot disease in pepper and tomato plants, which leads to economically important yield losses. This pathosystem has become a well-established model for studying bacterial infection strategies. Here, we present the whole-genome sequence of the pepper-pathogenic Xanthomonas campestris pv. vesicatoria strain 85-10, which comprises a 5.17-Mb circular chromosome and four plasmids. The genome has a high G+C content (64.75%) and signatures of extensive genome plasticity. Whole-genome comparisons revealed a gene order similar to both Xanthomonas axonopodis pv. citri and Xanthomonas campestris pv. campestris and a structure completely different from Xanthomonas oryzae pv. oryzae. A total of 548 coding sequences (12.2%) are unique to X. campestris pv. vesicatoria. In addition to a type III secretion system, which is essential for pathogenicity, the genome of strain 85-10 encodes all other types of protein secretion systems described so far in gram-negative bacteria. Remarkably, one of the putative type IV secretion systems encoded on the largest plasmid is similar to the Icm/Dot systems of the human pathogens Legionella pneumophila and Coxiella burnetii. Comparisons with other completely sequenced plant pathogens predicted six novel type III effector proteins and several other virulence factors, including adhesins, cell wall-degrading enzymes, and extracellular polysaccharides.
AB - The gram-negative plant-pathogenic bacterium Xanthomonas campestris pv. vesicatoria is the causative agent of bacterial spot disease in pepper and tomato plants, which leads to economically important yield losses. This pathosystem has become a well-established model for studying bacterial infection strategies. Here, we present the whole-genome sequence of the pepper-pathogenic Xanthomonas campestris pv. vesicatoria strain 85-10, which comprises a 5.17-Mb circular chromosome and four plasmids. The genome has a high G+C content (64.75%) and signatures of extensive genome plasticity. Whole-genome comparisons revealed a gene order similar to both Xanthomonas axonopodis pv. citri and Xanthomonas campestris pv. campestris and a structure completely different from Xanthomonas oryzae pv. oryzae. A total of 548 coding sequences (12.2%) are unique to X. campestris pv. vesicatoria. In addition to a type III secretion system, which is essential for pathogenicity, the genome of strain 85-10 encodes all other types of protein secretion systems described so far in gram-negative bacteria. Remarkably, one of the putative type IV secretion systems encoded on the largest plasmid is similar to the Icm/Dot systems of the human pathogens Legionella pneumophila and Coxiella burnetii. Comparisons with other completely sequenced plant pathogens predicted six novel type III effector proteins and several other virulence factors, including adhesins, cell wall-degrading enzymes, and extracellular polysaccharides.
UR - http://www.scopus.com/inward/record.url?scp=27144440067&partnerID=8YFLogxK
U2 - 10.1128/JB.187.21.7254-7266.2005
DO - 10.1128/JB.187.21.7254-7266.2005
M3 - Article
C2 - 16237009
AN - SCOPUS:27144440067
VL - 187
SP - 7254
EP - 7266
JO - Journal of Bacteriology
JF - Journal of Bacteriology
SN - 0021-9193
IS - 21
ER -