Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 1609-1619 |
| Seitenumfang | 11 |
| Fachzeitschrift | Journal of Biomedical Materials Research - Part A |
| Jahrgang | 93 |
| Ausgabenummer | 4 |
| Frühes Online-Datum | 13 Jan. 2010 |
| Publikationsstatus | Veröffentlicht - 15 Juni 2010 |
Abstract
MgCa0.8 cylinders (2.5 × 25 mm2) were coated with a magnesium-fluoride layer and implanted in the marrow cavities of both tibiae of 10 New Zealand White rabbits. The implantation duration was 3 and 6 months. The implants were clinically well tolerated. Micro-computed tomography revealed a new bone formation at the edges of the implants as well as an endosteal and periosteal remodeling. Using EDX-analysis, a calcium and phosphorus rich degradation layer could be found on the implant surface. It was covered by an incomplete layer containing fluoride. The analysis by weight before implantation and after 3 and 6 months, respectively, showed a slight decrease in volume in comparison to uncoated implants. When compared with uncoated implants, the mechanical properties of the coated implants exhibited a reduction in strength after 3 months. After 6 months, the strength of the coated implants was higher than that of uncoated cylinders.
ASJC Scopus Sachgebiete
- Werkstoffwissenschaften (insg.)
- Keramische und Verbundwerkstoffe
- Werkstoffwissenschaften (insg.)
- Biomaterialien
- Ingenieurwesen (insg.)
- Biomedizintechnik
- Werkstoffwissenschaften (insg.)
- Metalle und Legierungen
Zitieren
- Standard
- Harvard
- Apa
- Vancouver
- BibTex
- RIS
in: Journal of Biomedical Materials Research - Part A, Jahrgang 93, Nr. 4, 15.06.2010, S. 1609-1619.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Influence of a magnesium-fluoride coating of magnesium-based implants (MgCa0.8) on degradation in a rabbit model
AU - Thomann, Martina
AU - Krause, Christian
AU - Angrisani, Nina
AU - Bormann, Dirk
AU - Hassel, Thomas
AU - Windhagen, Henning
AU - Meyer-Lindenberg, Andrea
PY - 2010/6/15
Y1 - 2010/6/15
N2 - MgCa0.8 cylinders (2.5 × 25 mm2) were coated with a magnesium-fluoride layer and implanted in the marrow cavities of both tibiae of 10 New Zealand White rabbits. The implantation duration was 3 and 6 months. The implants were clinically well tolerated. Micro-computed tomography revealed a new bone formation at the edges of the implants as well as an endosteal and periosteal remodeling. Using EDX-analysis, a calcium and phosphorus rich degradation layer could be found on the implant surface. It was covered by an incomplete layer containing fluoride. The analysis by weight before implantation and after 3 and 6 months, respectively, showed a slight decrease in volume in comparison to uncoated implants. When compared with uncoated implants, the mechanical properties of the coated implants exhibited a reduction in strength after 3 months. After 6 months, the strength of the coated implants was higher than that of uncoated cylinders.
AB - MgCa0.8 cylinders (2.5 × 25 mm2) were coated with a magnesium-fluoride layer and implanted in the marrow cavities of both tibiae of 10 New Zealand White rabbits. The implantation duration was 3 and 6 months. The implants were clinically well tolerated. Micro-computed tomography revealed a new bone formation at the edges of the implants as well as an endosteal and periosteal remodeling. Using EDX-analysis, a calcium and phosphorus rich degradation layer could be found on the implant surface. It was covered by an incomplete layer containing fluoride. The analysis by weight before implantation and after 3 and 6 months, respectively, showed a slight decrease in volume in comparison to uncoated implants. When compared with uncoated implants, the mechanical properties of the coated implants exhibited a reduction in strength after 3 months. After 6 months, the strength of the coated implants was higher than that of uncoated cylinders.
KW - Biodegradation
KW - Fluoride layer
KW - Magnesium
KW - Osseointegration
KW - Surface treatment
UR - http://www.scopus.com/inward/record.url?scp=77951521928&partnerID=8YFLogxK
U2 - 10.1002/jbm.a.32639
DO - 10.1002/jbm.a.32639
M3 - Article
C2 - 20073078
AN - SCOPUS:77951521928
VL - 93
SP - 1609
EP - 1619
JO - Journal of Biomedical Materials Research - Part A
JF - Journal of Biomedical Materials Research - Part A
SN - 1549-3296
IS - 4
ER -