In Situ Microscopy for Online Monitoring of Enzymatic Processes

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

Organisationseinheiten

Externe Organisationen

  • Technische Universität Hamburg (TUHH)
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)837-840
Seitenumfang4
FachzeitschriftChemical Engineering and Technology
Jahrgang34
Ausgabenummer5
PublikationsstatusVeröffentlicht - 4 Apr. 2011

Abstract

In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.

ASJC Scopus Sachgebiete

Zitieren

In Situ Microscopy for Online Monitoring of Enzymatic Processes. / Prediger, A.; Bluma, A.; Höpfner, T. et al.
in: Chemical Engineering and Technology, Jahrgang 34, Nr. 5, 04.04.2011, S. 837-840.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Prediger, A, Bluma, A, Höpfner, T, Lindner, P, Beutel, S, Scheper, T, Müller, J, Hilterhaus, L & Liese, A 2011, 'In Situ Microscopy for Online Monitoring of Enzymatic Processes', Chemical Engineering and Technology, Jg. 34, Nr. 5, S. 837-840. https://doi.org/10.1002/ceat.201000563
Prediger, A., Bluma, A., Höpfner, T., Lindner, P., Beutel, S., Scheper, T., Müller, J., Hilterhaus, L., & Liese, A. (2011). In Situ Microscopy for Online Monitoring of Enzymatic Processes. Chemical Engineering and Technology, 34(5), 837-840. https://doi.org/10.1002/ceat.201000563
Prediger A, Bluma A, Höpfner T, Lindner P, Beutel S, Scheper T et al. In Situ Microscopy for Online Monitoring of Enzymatic Processes. Chemical Engineering and Technology. 2011 Apr 4;34(5):837-840. doi: 10.1002/ceat.201000563
Prediger, A. ; Bluma, A. ; Höpfner, T. et al. / In Situ Microscopy for Online Monitoring of Enzymatic Processes. in: Chemical Engineering and Technology. 2011 ; Jahrgang 34, Nr. 5. S. 837-840.
Download
@article{565901370b1e4dce9a793c813967b405,
title = "In Situ Microscopy for Online Monitoring of Enzymatic Processes",
abstract = "In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.",
keywords = "Enzyme catalysis, Image processing, In situ microscopy, Process monitoring",
author = "A. Prediger and A. Bluma and T. H{\"o}pfner and P. Lindner and S. Beutel and T. Scheper and J. M{\"u}ller and L. Hilterhaus and A. Liese",
year = "2011",
month = apr,
day = "4",
doi = "10.1002/ceat.201000563",
language = "English",
volume = "34",
pages = "837--840",
journal = "Chemical Engineering and Technology",
issn = "0930-7516",
publisher = "Wiley-VCH Verlag",
number = "5",

}

Download

TY - JOUR

T1 - In Situ Microscopy for Online Monitoring of Enzymatic Processes

AU - Prediger, A.

AU - Bluma, A.

AU - Höpfner, T.

AU - Lindner, P.

AU - Beutel, S.

AU - Scheper, T.

AU - Müller, J.

AU - Hilterhaus, L.

AU - Liese, A.

PY - 2011/4/4

Y1 - 2011/4/4

N2 - In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.

AB - In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.

KW - Enzyme catalysis

KW - Image processing

KW - In situ microscopy

KW - Process monitoring

UR - http://www.scopus.com/inward/record.url?scp=79955028015&partnerID=8YFLogxK

U2 - 10.1002/ceat.201000563

DO - 10.1002/ceat.201000563

M3 - Article

AN - SCOPUS:79955028015

VL - 34

SP - 837

EP - 840

JO - Chemical Engineering and Technology

JF - Chemical Engineering and Technology

SN - 0930-7516

IS - 5

ER -

Von denselben Autoren