Details
| Originalsprache | Englisch |
|---|---|
| Seiten (von - bis) | 3117-3123 |
| Seitenumfang | 7 |
| Fachzeitschrift | Reaction Chemistry & Engineering |
| Jahrgang | 8 |
| Ausgabenummer | 12 |
| Frühes Online-Datum | 4 Aug. 2023 |
| Publikationsstatus | Veröffentlicht - 2023 |
Abstract
Taking advantage of the unique properties of two-component flavo-monooxygenases and the ability of [Cp*Ir(bpy-OMe)H] + to transfer hydrides to reduce flavins, we extended the scope of the pH- and oxygen-robust iridium(iii)-complex to drive the enzymatic reaction of a FMN-dependent Baeyer-Villiger monooxygenase and a FAD-dependent styrene monooxygenase (respectively FPMO Group C and E), using formic acid as H-donor for NADH recycling.
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in: Reaction Chemistry & Engineering, Jahrgang 8, Nr. 12, 2023, S. 3117-3123.
Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review
}
TY - JOUR
T1 - Hybrid catalysis for enantioselective Baeyer–Villiger oxidation and stereoselective epoxidation
T2 - a Cp*Ir complex to fuel FMN and FAD reduction for flavoprotein monooxygenase modules
AU - Röllig, Robert
AU - Paul, Caroline E.
AU - Rousselot-Pailley, Pierre
AU - Kara, Selin
AU - Alphand, Véronique
N1 - Funding Information: The authors acknowledge funding from the European Union's Horizon 2020 MSCA ITN-EJD program under grant agreement No. 764920. They thank Prof. Dr D. Tischler for the plasmid bearing the SfStyA gene and Dr K. Duquesne for the plasmid bearing the 2,5-DKCMO gene.
PY - 2023
Y1 - 2023
N2 - Taking advantage of the unique properties of two-component flavo-monooxygenases and the ability of [Cp*Ir(bpy-OMe)H] + to transfer hydrides to reduce flavins, we extended the scope of the pH- and oxygen-robust iridium(iii)-complex to drive the enzymatic reaction of a FMN-dependent Baeyer-Villiger monooxygenase and a FAD-dependent styrene monooxygenase (respectively FPMO Group C and E), using formic acid as H-donor for NADH recycling.
AB - Taking advantage of the unique properties of two-component flavo-monooxygenases and the ability of [Cp*Ir(bpy-OMe)H] + to transfer hydrides to reduce flavins, we extended the scope of the pH- and oxygen-robust iridium(iii)-complex to drive the enzymatic reaction of a FMN-dependent Baeyer-Villiger monooxygenase and a FAD-dependent styrene monooxygenase (respectively FPMO Group C and E), using formic acid as H-donor for NADH recycling.
UR - http://www.scopus.com/inward/record.url?scp=85170659033&partnerID=8YFLogxK
U2 - 10.1039/d3re00411b
DO - 10.1039/d3re00411b
M3 - Article
VL - 8
SP - 3117
EP - 3123
JO - Reaction Chemistry & Engineering
JF - Reaction Chemistry & Engineering
IS - 12
ER -