Healthcare costs associated with breast cancer in Germany: a claims data analysis

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Autoren

  • Kristine Kreis
  • Marika Plöthner
  • Torben Schmidt
  • Richard Seufert
  • Katharina Schreeb
  • Veronika Jahndel
  • Sylke Maas
  • Alexander Kuhlmann
  • Jan Zeidler
  • Anja Schramm

Externe Organisationen

  • AOK Bayern - Die Gesundheitskasse, Zentrale
  • BioNTech SE
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Details

OriginalspracheEnglisch
Seiten (von - bis)451-464
Seitenumfang14
FachzeitschriftEuropean Journal of Health Economics
Jahrgang21
Ausgabenummer3
Frühes Online-Datum2 Jan. 2020
PublikationsstatusVeröffentlicht - Apr. 2020

Abstract

Purpose: This study estimates the healthcare costs associated with breast cancer (BC) for different treatment phases (initial, intermediate, terminal) in Germany from the payer’s perspective. Methods: The analysis uses claims data from the AOK Bayern covering 2011–2014 for continuously insured BC patients identified through inpatient and outpatient diagnoses. We calculate the healthcare costs attributable to BC using a control group design comparing the target population to a 1:2 matched control group adjusted for age, gender, and comorbidities. For incident and prevalent BC cases, we calculate age-standardized phase-specific incremental costs stratified by cost domain. Results: The initial, intermediate, and terminal phases comprise 3841, 28,315, and 1767 BC cases, respectively. BC-related incremental costs follow a u-shaped curve, with costs highest near diagnosis and death, and lower in between. With average costs of €33,237 per incident and €28,211 per prevalent case in the remaining 11 months before death, the highest BC-related incremental healthcare costs can be found in the terminal phase. In the initial phase, there were mean incremental costs of €21,455 the first 11 months after diagnosis. In the intermediate phase, incremental costs totaled €2851 per incident and €2387 per prevalent case per year. Healthcare costs decreased with age in most phases. The cost drivers depend on the treatment phase, with cytostatic drugs and inpatient treatment showing the highest economic impact in most phases. Conclusion: The study concludes that BC care costs impose a relevant economic burden on statutory health insurance and vary substantially depending on the treatment phase.

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Healthcare costs associated with breast cancer in Germany: a claims data analysis. / Kreis, Kristine; Plöthner, Marika; Schmidt, Torben et al.
in: European Journal of Health Economics, Jahrgang 21, Nr. 3, 04.2020, S. 451-464.

Publikation: Beitrag in FachzeitschriftArtikelForschungPeer-Review

Kreis, K, Plöthner, M, Schmidt, T, Seufert, R, Schreeb, K, Jahndel, V, Maas, S, Kuhlmann, A, Zeidler, J & Schramm, A 2020, 'Healthcare costs associated with breast cancer in Germany: a claims data analysis', European Journal of Health Economics, Jg. 21, Nr. 3, S. 451-464. https://doi.org/10.1007/s10198-019-01148-w
Kreis, K., Plöthner, M., Schmidt, T., Seufert, R., Schreeb, K., Jahndel, V., Maas, S., Kuhlmann, A., Zeidler, J., & Schramm, A. (2020). Healthcare costs associated with breast cancer in Germany: a claims data analysis. European Journal of Health Economics, 21(3), 451-464. https://doi.org/10.1007/s10198-019-01148-w
Kreis K, Plöthner M, Schmidt T, Seufert R, Schreeb K, Jahndel V et al. Healthcare costs associated with breast cancer in Germany: a claims data analysis. European Journal of Health Economics. 2020 Apr;21(3):451-464. Epub 2020 Jan 2. doi: 10.1007/s10198-019-01148-w
Kreis, Kristine ; Plöthner, Marika ; Schmidt, Torben et al. / Healthcare costs associated with breast cancer in Germany : a claims data analysis. in: European Journal of Health Economics. 2020 ; Jahrgang 21, Nr. 3. S. 451-464.
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abstract = "Purpose: This study estimates the healthcare costs associated with breast cancer (BC) for different treatment phases (initial, intermediate, terminal) in Germany from the payer{\textquoteright}s perspective. Methods: The analysis uses claims data from the AOK Bayern covering 2011–2014 for continuously insured BC patients identified through inpatient and outpatient diagnoses. We calculate the healthcare costs attributable to BC using a control group design comparing the target population to a 1:2 matched control group adjusted for age, gender, and comorbidities. For incident and prevalent BC cases, we calculate age-standardized phase-specific incremental costs stratified by cost domain. Results: The initial, intermediate, and terminal phases comprise 3841, 28,315, and 1767 BC cases, respectively. BC-related incremental costs follow a u-shaped curve, with costs highest near diagnosis and death, and lower in between. With average costs of €33,237 per incident and €28,211 per prevalent case in the remaining 11 months before death, the highest BC-related incremental healthcare costs can be found in the terminal phase. In the initial phase, there were mean incremental costs of €21,455 the first 11 months after diagnosis. In the intermediate phase, incremental costs totaled €2851 per incident and €2387 per prevalent case per year. Healthcare costs decreased with age in most phases. The cost drivers depend on the treatment phase, with cytostatic drugs and inpatient treatment showing the highest economic impact in most phases. Conclusion: The study concludes that BC care costs impose a relevant economic burden on statutory health insurance and vary substantially depending on the treatment phase.",
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TY - JOUR

T1 - Healthcare costs associated with breast cancer in Germany

T2 - a claims data analysis

AU - Kreis, Kristine

AU - Plöthner, Marika

AU - Schmidt, Torben

AU - Seufert, Richard

AU - Schreeb, Katharina

AU - Jahndel, Veronika

AU - Maas, Sylke

AU - Kuhlmann, Alexander

AU - Zeidler, Jan

AU - Schramm, Anja

N1 - Funding information: This study was supported by the Federal Ministry of Education and Research (Grant number 13GW0078B).

PY - 2020/4

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N2 - Purpose: This study estimates the healthcare costs associated with breast cancer (BC) for different treatment phases (initial, intermediate, terminal) in Germany from the payer’s perspective. Methods: The analysis uses claims data from the AOK Bayern covering 2011–2014 for continuously insured BC patients identified through inpatient and outpatient diagnoses. We calculate the healthcare costs attributable to BC using a control group design comparing the target population to a 1:2 matched control group adjusted for age, gender, and comorbidities. For incident and prevalent BC cases, we calculate age-standardized phase-specific incremental costs stratified by cost domain. Results: The initial, intermediate, and terminal phases comprise 3841, 28,315, and 1767 BC cases, respectively. BC-related incremental costs follow a u-shaped curve, with costs highest near diagnosis and death, and lower in between. With average costs of €33,237 per incident and €28,211 per prevalent case in the remaining 11 months before death, the highest BC-related incremental healthcare costs can be found in the terminal phase. In the initial phase, there were mean incremental costs of €21,455 the first 11 months after diagnosis. In the intermediate phase, incremental costs totaled €2851 per incident and €2387 per prevalent case per year. Healthcare costs decreased with age in most phases. The cost drivers depend on the treatment phase, with cytostatic drugs and inpatient treatment showing the highest economic impact in most phases. Conclusion: The study concludes that BC care costs impose a relevant economic burden on statutory health insurance and vary substantially depending on the treatment phase.

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KW - Disease cost

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SN - 1618-7598

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