Details
| Originalsprache | Englisch |
|---|---|
| Titel des Sammelwerks | Regulated Proteolysis in Microorganisms |
| Seiten | 73-103 |
| Seitenumfang | 31 |
| ISBN (elektronisch) | 978-94-007-5940-4 |
| Publikationsstatus | Veröffentlicht - 8 Feb. 2013 |
Publikationsreihe
| Name | Subcellular Biochemistry |
|---|---|
| Herausgeber (Verlag) | Plenum Publishers |
| ISSN (Print) | 0306-0225 |
Abstract
The soil-dwelling bacterium Bacillus subtilis is widely used as a model organism to study the Gram-positive branch of Bacteria. A variety of different developmental pathways, such as endospore formation, genetic competence, motility, swarming and bio film formation, have been studied in this organism. These processes are intricately connected and regulated by networks containing e.g. alternative sigma factors, two-component systems and other regulators. Importantly, in some of these regulatory networks the activity of important regulatory factors is controlled by proteases. Furthermore, together with chaperones, the same proteases constitute the cellular protein quality control (PQC) network, which plays a crucial role in protein homeostasis and stress tolerance of this organism. In this review, we will present the current knowledge on regulatory and general proteolysis in B. subtilis and discuss its involvement in developmental pathways and cellular stress management.
ASJC Scopus Sachgebiete
- Biochemie, Genetik und Molekularbiologie (insg.)
- Biochemie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Molekularbiologie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Zellbiologie
- Biochemie, Genetik und Molekularbiologie (insg.)
- Krebsforschung
Ziele für nachhaltige Entwicklung
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- BibTex
- RIS
Regulated Proteolysis in Microorganisms. 2013. S. 73-103 (Subcellular Biochemistry).
Publikation: Beitrag in Buch/Bericht/Sammelwerk/Konferenzband › Beitrag in Buch/Sammelwerk › Forschung › Peer-Review
}
TY - CHAP
T1 - General and Regulatory Proteolysis in Bacillus subtilis
AU - Molière, Noël
AU - Turgay, Kürşad
N1 - Funding information: The work in the Laboratory of KT is supported by the Deutsche Forschungsgemeinschaft.
PY - 2013/2/8
Y1 - 2013/2/8
N2 - The soil-dwelling bacterium Bacillus subtilis is widely used as a model organism to study the Gram-positive branch of Bacteria. A variety of different developmental pathways, such as endospore formation, genetic competence, motility, swarming and bio film formation, have been studied in this organism. These processes are intricately connected and regulated by networks containing e.g. alternative sigma factors, two-component systems and other regulators. Importantly, in some of these regulatory networks the activity of important regulatory factors is controlled by proteases. Furthermore, together with chaperones, the same proteases constitute the cellular protein quality control (PQC) network, which plays a crucial role in protein homeostasis and stress tolerance of this organism. In this review, we will present the current knowledge on regulatory and general proteolysis in B. subtilis and discuss its involvement in developmental pathways and cellular stress management.
AB - The soil-dwelling bacterium Bacillus subtilis is widely used as a model organism to study the Gram-positive branch of Bacteria. A variety of different developmental pathways, such as endospore formation, genetic competence, motility, swarming and bio film formation, have been studied in this organism. These processes are intricately connected and regulated by networks containing e.g. alternative sigma factors, two-component systems and other regulators. Importantly, in some of these regulatory networks the activity of important regulatory factors is controlled by proteases. Furthermore, together with chaperones, the same proteases constitute the cellular protein quality control (PQC) network, which plays a crucial role in protein homeostasis and stress tolerance of this organism. In this review, we will present the current knowledge on regulatory and general proteolysis in B. subtilis and discuss its involvement in developmental pathways and cellular stress management.
UR - http://www.scopus.com/inward/record.url?scp=84881486320&partnerID=8YFLogxK
U2 - 10.1007/978-94-007-5940-4_4
DO - 10.1007/978-94-007-5940-4_4
M3 - Contribution to book/anthology
C2 - 23479438
AN - SCOPUS:84881486320
T3 - Subcellular Biochemistry
SP - 73
EP - 103
BT - Regulated Proteolysis in Microorganisms
ER -