Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Autoren

  • Esther Vázquez
  • José L. Corchero
  • Joan F. Burgueño
  • Joaquin Seras-Franzoso
  • Ana Kosoy
  • Ramon Bosser
  • Rosa Mendoza
  • Joan Marc Martínez-Láinez
  • Ursula Rinas
  • Ester Fernández
  • Luis Ruiz-Avila
  • Elena García-Fruitõs
  • Antonio Villaverde

Organisationseinheiten

Externe Organisationen

  • Universidad Autónoma de Barcelona (UAB)
  • Centros de Investigacion Biomedica en Red - CIBER
  • Janus Development, SL
  • Helmholtz-Zentrum für Infektionsforschung GmbH (HZI)
Forschungs-netzwerk anzeigen

Details

OriginalspracheEnglisch
Seiten (von - bis)1742-1747
Seitenumfang6
FachzeitschriftAdvanced materials
Jahrgang24
Ausgabenummer13
Frühes Online-Datum13 März 2012
PublikationsstatusVeröffentlicht - 3 Apr. 2012

Abstract

Inclusion bodies (50-500 nm in diameter) produced in recombinant bacteria can be engineered to contain functional proteins with therapeutic potential. Upon exposure, these protein particles are efficiently internalized by mammalian cells and promote recovery from diverse stresses. Being fully biocompatible, inclusion bodies are a novel platform, as tailored nanopills, for sustained drug release in advanced cell therapies.

ASJC Scopus Sachgebiete

Zitieren

Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies. / Vázquez, Esther; Corchero, José L.; Burgueño, Joan F. et al.
in: Advanced materials, Jahrgang 24, Nr. 13, 03.04.2012, S. 1742-1747.

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Vázquez, E, Corchero, JL, Burgueño, JF, Seras-Franzoso, J, Kosoy, A, Bosser, R, Mendoza, R, Martínez-Láinez, JM, Rinas, U, Fernández, E, Ruiz-Avila, L, García-Fruitõs, E & Villaverde, A 2012, 'Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies', Advanced materials, Jg. 24, Nr. 13, S. 1742-1747. https://doi.org/10.1002/adma.201104330
Vázquez, E., Corchero, J. L., Burgueño, J. F., Seras-Franzoso, J., Kosoy, A., Bosser, R., Mendoza, R., Martínez-Láinez, J. M., Rinas, U., Fernández, E., Ruiz-Avila, L., García-Fruitõs, E., & Villaverde, A. (2012). Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies. Advanced materials, 24(13), 1742-1747. https://doi.org/10.1002/adma.201104330
Vázquez E, Corchero JL, Burgueño JF, Seras-Franzoso J, Kosoy A, Bosser R et al. Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies. Advanced materials. 2012 Apr 3;24(13):1742-1747. Epub 2012 Mär 13. doi: 10.1002/adma.201104330
Vázquez, Esther ; Corchero, José L. ; Burgueño, Joan F. et al. / Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies. in: Advanced materials. 2012 ; Jahrgang 24, Nr. 13. S. 1742-1747.
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AU - Burgueño, Joan F.

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AU - Bosser, Ramon

AU - Mendoza, Rosa

AU - Martínez-Láinez, Joan Marc

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AU - Fernández, Ester

AU - Ruiz-Avila, Luis

AU - García-Fruitõs, Elena

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